Affordable Biocidal Ultraviolet Cured Cuprous Oxide Filled Vat Photopolymerization Resin Nanocomposites with Enhanced Mechanical Properties

In this study, Cuprous Oxide (Cu<sub>2</sub>O), known for its mechanism against bacteria, was used as filler to induce biocidal properties on a common commercial resin stereolithography (SLA) 3D printing resin. The aim was to develop nanocomposites suitable for the SLA process with a low...

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Main Authors: Markos Petousis, Nectarios Vidakis, Emmanuel Velidakis, John D. Kechagias, Constantine N. David, Stefanos Papadakis, Nikolaos Mountakis
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomimetics
Subjects:
Online Access:https://www.mdpi.com/2313-7673/7/1/12
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author Markos Petousis
Nectarios Vidakis
Emmanuel Velidakis
John D. Kechagias
Constantine N. David
Stefanos Papadakis
Nikolaos Mountakis
author_facet Markos Petousis
Nectarios Vidakis
Emmanuel Velidakis
John D. Kechagias
Constantine N. David
Stefanos Papadakis
Nikolaos Mountakis
author_sort Markos Petousis
collection DOAJ
description In this study, Cuprous Oxide (Cu<sub>2</sub>O), known for its mechanism against bacteria, was used as filler to induce biocidal properties on a common commercial resin stereolithography (SLA) 3D printing resin. The aim was to develop nanocomposites suitable for the SLA process with a low-cost process that mimic host defense peptides (HDPs). Such materials have a huge economic and societal influence on the global technological war on illness and exploiting 3D printing characteristics is an additional asset for these materials. Their mechanical performance was also investigated with tensile, flexural, Charpy’s impact, and Vickers microhardness tests. Morphological analysis was performed through scanning electron microscopy (SEM), atomic force microscopy (AFM), and energy-dispersive X-ray spectroscopy (EDS) analysis, while the thermal behavior was studied through Thermogravimetric Analysis (TGA). The antibacterial activity of the fabricated nanocomposites was investigated using a screening agar well diffusion method, for a gram-negative and a gram-positive bacterium. Three-dimensional printed nanocomposites exhibited antibacterial performance in all loadings studied, while their mechanical enhancement was approximately 20% even at low filler loadings, revealing a multi-functional performance and a potential of Cuprous Oxide implementation in SLA resin matrices for engineering and medical applications.
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spelling doaj.art-abf7daffdeb54bd7bd3588a879fde79d2023-11-24T00:34:17ZengMDPI AGBiomimetics2313-76732022-01-01711210.3390/biomimetics7010012Affordable Biocidal Ultraviolet Cured Cuprous Oxide Filled Vat Photopolymerization Resin Nanocomposites with Enhanced Mechanical PropertiesMarkos Petousis0Nectarios Vidakis1Emmanuel Velidakis2John D. Kechagias3Constantine N. David4Stefanos Papadakis5Nikolaos Mountakis6Mechanical Engineering Department, Hellenic Mediterranean University, Estavromenos, 71410 Heraklion, GreeceMechanical Engineering Department, Hellenic Mediterranean University, Estavromenos, 71410 Heraklion, GreeceMechanical Engineering Department, Hellenic Mediterranean University, Estavromenos, 71410 Heraklion, GreeceGeneral Department, University of Thessaly, 41500 Larissa, GreeceManufacturing Technology & Production Systems Laboratory, School of Engineering, International Hellenic University, Serres Campus, 62124 Serres, GreeceBiology Department, University of Crete, Voutes University Campus, P.O. Box 2208, 70013 Heraklion, GreeceMechanical Engineering Department, Hellenic Mediterranean University, Estavromenos, 71410 Heraklion, GreeceIn this study, Cuprous Oxide (Cu<sub>2</sub>O), known for its mechanism against bacteria, was used as filler to induce biocidal properties on a common commercial resin stereolithography (SLA) 3D printing resin. The aim was to develop nanocomposites suitable for the SLA process with a low-cost process that mimic host defense peptides (HDPs). Such materials have a huge economic and societal influence on the global technological war on illness and exploiting 3D printing characteristics is an additional asset for these materials. Their mechanical performance was also investigated with tensile, flexural, Charpy’s impact, and Vickers microhardness tests. Morphological analysis was performed through scanning electron microscopy (SEM), atomic force microscopy (AFM), and energy-dispersive X-ray spectroscopy (EDS) analysis, while the thermal behavior was studied through Thermogravimetric Analysis (TGA). The antibacterial activity of the fabricated nanocomposites was investigated using a screening agar well diffusion method, for a gram-negative and a gram-positive bacterium. Three-dimensional printed nanocomposites exhibited antibacterial performance in all loadings studied, while their mechanical enhancement was approximately 20% even at low filler loadings, revealing a multi-functional performance and a potential of Cuprous Oxide implementation in SLA resin matrices for engineering and medical applications.https://www.mdpi.com/2313-7673/7/1/12stereolithography (SLA)3D printingantibacterialadditive manufacturing (AM)Cuprous Oxideresin
spellingShingle Markos Petousis
Nectarios Vidakis
Emmanuel Velidakis
John D. Kechagias
Constantine N. David
Stefanos Papadakis
Nikolaos Mountakis
Affordable Biocidal Ultraviolet Cured Cuprous Oxide Filled Vat Photopolymerization Resin Nanocomposites with Enhanced Mechanical Properties
Biomimetics
stereolithography (SLA)
3D printing
antibacterial
additive manufacturing (AM)
Cuprous Oxide
resin
title Affordable Biocidal Ultraviolet Cured Cuprous Oxide Filled Vat Photopolymerization Resin Nanocomposites with Enhanced Mechanical Properties
title_full Affordable Biocidal Ultraviolet Cured Cuprous Oxide Filled Vat Photopolymerization Resin Nanocomposites with Enhanced Mechanical Properties
title_fullStr Affordable Biocidal Ultraviolet Cured Cuprous Oxide Filled Vat Photopolymerization Resin Nanocomposites with Enhanced Mechanical Properties
title_full_unstemmed Affordable Biocidal Ultraviolet Cured Cuprous Oxide Filled Vat Photopolymerization Resin Nanocomposites with Enhanced Mechanical Properties
title_short Affordable Biocidal Ultraviolet Cured Cuprous Oxide Filled Vat Photopolymerization Resin Nanocomposites with Enhanced Mechanical Properties
title_sort affordable biocidal ultraviolet cured cuprous oxide filled vat photopolymerization resin nanocomposites with enhanced mechanical properties
topic stereolithography (SLA)
3D printing
antibacterial
additive manufacturing (AM)
Cuprous Oxide
resin
url https://www.mdpi.com/2313-7673/7/1/12
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