Clinical features of fundus lesions of 74 patients with acquired immunodeficiency syndrome in Shenyang
AIM: To investigate the clinical features and factors of fundus lesions in patients with acquired immunodeficiency syndrome(AIDS)in Shenyang and the relationship between fundus lesions and CD4+T cell count.METHODS: Retrospective case study. A total of 74 cases with AIDS who were treated in the Centr...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2023-03-01
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| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2023/3/202303031.pdf |
| _version_ | 1811160888980275200 |
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| author | Xin-Xin Sun Bai-Qing Shi Chang-Lin Sun |
| author_facet | Xin-Xin Sun Bai-Qing Shi Chang-Lin Sun |
| author_sort | Xin-Xin Sun |
| collection | DOAJ |
| description | AIM: To investigate the clinical features and factors of fundus lesions in patients with acquired immunodeficiency syndrome(AIDS)in Shenyang and the relationship between fundus lesions and CD4+T cell count.METHODS: Retrospective case study. A total of 74 cases with AIDS who were treated in the Central Hospital of Liaoning Electric Power Supply Co., Ltd., from January 2021 to December 2021 were selected. The fundus manifestation and CD4+T cell count of the patients were analyzed.RESULTS: The total detection rate of fundus lesions in AIDS patients was 58%. CD4+T cell count in the patients with fundus lesions was significantly lower than that in the patients with normal fundus [29(6, 55)/μL vs. 76(35, 103)/μL, P<0.01]. The rate of fundus lesions was the highest in the patients with CD4+T cell count ≤ 50/μL(74%). Logistic regression analysis showed that as the CD4+T cell count increased, the incidence of fundus lesions decreased(OR=0.977, 95%CI 0.964～0.991, P<0.01).CONCLUSION: Fundus lesions in AIDS patients related to CD4+T cell count. Decreasing CD4+T cell count was a risk factor of fundus lesions for AIDS patients. Routine fundus examination is important for the early diagnosis of fundus lesions in AIDS patients. |
| first_indexed | 2024-04-10T06:06:28Z |
| format | Article |
| id | doaj.art-abf988f3d721429bad4f4719724f3451 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 |
| language | English |
| last_indexed | 2024-04-10T06:06:28Z |
| publishDate | 2023-03-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-abf988f3d721429bad4f4719724f34512023-03-03T03:10:42ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232023-03-0123350851110.3980/j.issn.1672-5123.2023.3.31202303031Clinical features of fundus lesions of 74 patients with acquired immunodeficiency syndrome in ShenyangXin-Xin Sun0Bai-Qing Shi1Chang-Lin Sun2Department of Ophthalmology,Central Hospital of Liaoning Electric Power Supply Co., Ltd., Shenyang 110005, Liaoning Province, ChinaDepartment of Ophthalmology,Central Hospital of Liaoning Electric Power Supply Co., Ltd., Shenyang 110005, Liaoning Province, ChinaDepartment of Ophthalmology,Central Hospital of Liaoning Electric Power Supply Co., Ltd., Shenyang 110005, Liaoning Province, ChinaAIM: To investigate the clinical features and factors of fundus lesions in patients with acquired immunodeficiency syndrome(AIDS)in Shenyang and the relationship between fundus lesions and CD4+T cell count.METHODS: Retrospective case study. A total of 74 cases with AIDS who were treated in the Central Hospital of Liaoning Electric Power Supply Co., Ltd., from January 2021 to December 2021 were selected. The fundus manifestation and CD4+T cell count of the patients were analyzed.RESULTS: The total detection rate of fundus lesions in AIDS patients was 58%. CD4+T cell count in the patients with fundus lesions was significantly lower than that in the patients with normal fundus [29(6, 55)/μL vs. 76(35, 103)/μL, P<0.01]. The rate of fundus lesions was the highest in the patients with CD4+T cell count ≤ 50/μL(74%). Logistic regression analysis showed that as the CD4+T cell count increased, the incidence of fundus lesions decreased(OR=0.977, 95%CI 0.964～0.991, P<0.01).CONCLUSION: Fundus lesions in AIDS patients related to CD4+T cell count. Decreasing CD4+T cell count was a risk factor of fundus lesions for AIDS patients. Routine fundus examination is important for the early diagnosis of fundus lesions in AIDS patients.http://ies.ijo.cn/cn_publish/2023/3/202303031.pdfacquired immunodeficiency syndromefundus lesionscd4+t cellcytomegalovirusrisk factor |
| spellingShingle | Xin-Xin Sun Bai-Qing Shi Chang-Lin Sun Clinical features of fundus lesions of 74 patients with acquired immunodeficiency syndrome in Shenyang Guoji Yanke Zazhi acquired immunodeficiency syndrome fundus lesions cd4+t cell cytomegalovirus risk factor |
| title | Clinical features of fundus lesions of 74 patients with acquired immunodeficiency syndrome in Shenyang |
| title_full | Clinical features of fundus lesions of 74 patients with acquired immunodeficiency syndrome in Shenyang |
| title_fullStr | Clinical features of fundus lesions of 74 patients with acquired immunodeficiency syndrome in Shenyang |
| title_full_unstemmed | Clinical features of fundus lesions of 74 patients with acquired immunodeficiency syndrome in Shenyang |
| title_short | Clinical features of fundus lesions of 74 patients with acquired immunodeficiency syndrome in Shenyang |
| title_sort | clinical features of fundus lesions of 74 patients with acquired immunodeficiency syndrome in shenyang |
| topic | acquired immunodeficiency syndrome fundus lesions cd4+t cell cytomegalovirus risk factor |
| url | http://ies.ijo.cn/cn_publish/2023/3/202303031.pdf |
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