Anaplastic mammary carcinoma in a captive jaguar (Panthera onca)
ABSTRACT A captive female of jaguar (Panthera onca), 12 years old, presenting an 8-day history of anorexia and lethargy, died in its enclosure in Manaus (Amazonas, Brazil). The necropsy revealed an abdominal multinodular ventral plaque into the mammary region. Additionally, in several locations of t...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Instituto Nacional de Pesquisas da Amazônia
2023-11-01
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| Series: | Acta Amazonica |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672023000400281&lng=en&tlng=en |
| _version_ | 1797628735238701056 |
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| author | Camila TOCHETTO Guilherme Augusto MARIETTO GONÇALVES Diogo Souza ZANONI Renato Lemos PEREIRA Gisele Torres Clímaco de ARAÚJO Renan Mori ROCHA Bruna Carolina ULSENHEIMER Alexandre Alberto TONIN |
| author_facet | Camila TOCHETTO Guilherme Augusto MARIETTO GONÇALVES Diogo Souza ZANONI Renato Lemos PEREIRA Gisele Torres Clímaco de ARAÚJO Renan Mori ROCHA Bruna Carolina ULSENHEIMER Alexandre Alberto TONIN |
| author_sort | Camila TOCHETTO |
| collection | DOAJ |
| description | ABSTRACT A captive female of jaguar (Panthera onca), 12 years old, presenting an 8-day history of anorexia and lethargy, died in its enclosure in Manaus (Amazonas, Brazil). The necropsy revealed an abdominal multinodular ventral plaque into the mammary region. Additionally, in several locations of the subcutaneous tissue, there were multiple metastatic nodules of firm texture. Metastases were also observed in the lymph nodes, heart and lungs. The immunohistochemistry results revealed the cytoplasmic staining for cytokeratin on neoplastic cells, mild staining (+) for E-cadherin, moderate staining (++) for estrogen and progesterone receptors, and about 50 to 70% of staining for Ki-67. The neoplastic cells were negative for vimentin staining. Therefore, the histopathological examination led to a diagnosis of metastatic anaplastic mammary carcinoma, which is an unusual condition in wild felines. |
| first_indexed | 2024-03-11T10:44:17Z |
| format | Article |
| id | doaj.art-abf99c6650054c96948cbd11e0004133 |
| institution | Directory Open Access Journal |
| issn | 0044-5967 |
| language | English |
| last_indexed | 2024-03-11T10:44:17Z |
| publishDate | 2023-11-01 |
| publisher | Instituto Nacional de Pesquisas da Amazônia |
| record_format | Article |
| series | Acta Amazonica |
| spelling | doaj.art-abf99c6650054c96948cbd11e00041332023-11-14T07:52:00ZengInstituto Nacional de Pesquisas da AmazôniaActa Amazonica0044-59672023-11-0153428128410.1590/1809-4392202300201Anaplastic mammary carcinoma in a captive jaguar (Panthera onca)Camila TOCHETTOGuilherme Augusto MARIETTO GONÇALVESDiogo Souza ZANONIRenato Lemos PEREIRAGisele Torres Clímaco de ARAÚJORenan Mori ROCHABruna Carolina ULSENHEIMERAlexandre Alberto TONINhttps://orcid.org/0000-0002-4236-8976ABSTRACT A captive female of jaguar (Panthera onca), 12 years old, presenting an 8-day history of anorexia and lethargy, died in its enclosure in Manaus (Amazonas, Brazil). The necropsy revealed an abdominal multinodular ventral plaque into the mammary region. Additionally, in several locations of the subcutaneous tissue, there were multiple metastatic nodules of firm texture. Metastases were also observed in the lymph nodes, heart and lungs. The immunohistochemistry results revealed the cytoplasmic staining for cytokeratin on neoplastic cells, mild staining (+) for E-cadherin, moderate staining (++) for estrogen and progesterone receptors, and about 50 to 70% of staining for Ki-67. The neoplastic cells were negative for vimentin staining. Therefore, the histopathological examination led to a diagnosis of metastatic anaplastic mammary carcinoma, which is an unusual condition in wild felines.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672023000400281&lng=en&tlng=enAmazonFelidaeneoplastic diseasewild feline |
| spellingShingle | Camila TOCHETTO Guilherme Augusto MARIETTO GONÇALVES Diogo Souza ZANONI Renato Lemos PEREIRA Gisele Torres Clímaco de ARAÚJO Renan Mori ROCHA Bruna Carolina ULSENHEIMER Alexandre Alberto TONIN Anaplastic mammary carcinoma in a captive jaguar (Panthera onca) Acta Amazonica Amazon Felidae neoplastic disease wild feline |
| title | Anaplastic mammary carcinoma in a captive jaguar (Panthera onca) |
| title_full | Anaplastic mammary carcinoma in a captive jaguar (Panthera onca) |
| title_fullStr | Anaplastic mammary carcinoma in a captive jaguar (Panthera onca) |
| title_full_unstemmed | Anaplastic mammary carcinoma in a captive jaguar (Panthera onca) |
| title_short | Anaplastic mammary carcinoma in a captive jaguar (Panthera onca) |
| title_sort | anaplastic mammary carcinoma in a captive jaguar panthera onca |
| topic | Amazon Felidae neoplastic disease wild feline |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672023000400281&lng=en&tlng=en |
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