Improving cervical cancer screening in Mexico: results from the Morelos HPV Study

OBJECTIVE: The purpose of this paper is to describe some of the results of the Morelos HPV Study. The main objective of the Morelos HPV Study is to evaluate the use of human papillomavirus (HPV) DNA testing, as compared to the Papanicolaou (Pap) test, for cervical cancer (CC) screening. MATERIAL AND...

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Main Authors: Flores Yvonne, Bishai David, Lazcano Eduardo, Shah Keerti, Lörincz Attila, Hernández Mauricio, Salmerón Jorge, Ferris Daron, Hernández Pilar, Sherman Mark E, Ronnett Brigitte M, Carmona Enrique, Antúnez Alfredo, Manzanares Horacio, Uribe Mario, Pérez-Cuevas Ricardo, Leyva Ahideé, Yunes Elsa
Format: Article
Language:English
Published: Instituto Nacional de Salud Pública 2003-01-01
Series:Salud Pública de México
Subjects:
Online Access:http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0036-36342003000900013
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author Flores Yvonne
Bishai David
Lazcano Eduardo
Shah Keerti
Lörincz Attila
Hernández Mauricio
Salmerón Jorge
Ferris Daron
Hernández Pilar
Sherman Mark E
Ronnett Brigitte M
Carmona Enrique
Antúnez Alfredo
Manzanares Horacio
Uribe Mario
Pérez-Cuevas Ricardo
Leyva Ahideé
Yunes Elsa
author_facet Flores Yvonne
Bishai David
Lazcano Eduardo
Shah Keerti
Lörincz Attila
Hernández Mauricio
Salmerón Jorge
Ferris Daron
Hernández Pilar
Sherman Mark E
Ronnett Brigitte M
Carmona Enrique
Antúnez Alfredo
Manzanares Horacio
Uribe Mario
Pérez-Cuevas Ricardo
Leyva Ahideé
Yunes Elsa
author_sort Flores Yvonne
collection DOAJ
description OBJECTIVE: The purpose of this paper is to describe some of the results of the Morelos HPV Study. The main objective of the Morelos HPV Study is to evaluate the use of human papillomavirus (HPV) DNA testing, as compared to the Papanicolaou (Pap) test, for cervical cancer (CC) screening. MATERIAL AND METHODS: The Morelos HPV Study is currently being conducted in Mexico, to examine the possibility of using HPV testing for CC screening. The HPV testing of self-collected vaginal and clinician-collected cervical specimens was evaluated as part of this study. The acceptability of the HPV testing of self-collected specimens was compared to that of the Pap test. A cost-effectiveness analysis (CEA) and cost-benefit analysis (CBA) was also performed. RESULTS: The Morelos HPV Study results indicate that HPV testing has a greater sensitivity to detect cervical intraepithelial neoplasia (CIN) 2/3 and CC than the Pap test. Our results also indicate an over-all lower acceptability of the Pap test as compared to the self-collected procedure. The results of the CEA and CBA indicate that screening women between the ages of 20-80 for CC using some type of HPV testing is always more cost-effective than screening for CC using the Pap test. CONCLUSIONS: Our results suggest that self- and clinician-collected HPV testing could be used in CC prevention programs, as an effective complement or substitute for the Pap test.
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spelling doaj.art-abfbdfaf6f1f47a5968380d9599ae61a2022-12-22T01:19:07ZengInstituto Nacional de Salud PúblicaSalud Pública de México0036-36342003-01-0145suppl.3388398Improving cervical cancer screening in Mexico: results from the Morelos HPV StudyFlores YvonneBishai DavidLazcano EduardoShah KeertiLörincz AttilaHernández MauricioSalmerón JorgeFerris DaronHernández PilarSherman Mark ERonnett Brigitte MCarmona EnriqueAntúnez AlfredoManzanares HoracioUribe MarioPérez-Cuevas RicardoLeyva AhideéYunes ElsaOBJECTIVE: The purpose of this paper is to describe some of the results of the Morelos HPV Study. The main objective of the Morelos HPV Study is to evaluate the use of human papillomavirus (HPV) DNA testing, as compared to the Papanicolaou (Pap) test, for cervical cancer (CC) screening. MATERIAL AND METHODS: The Morelos HPV Study is currently being conducted in Mexico, to examine the possibility of using HPV testing for CC screening. The HPV testing of self-collected vaginal and clinician-collected cervical specimens was evaluated as part of this study. The acceptability of the HPV testing of self-collected specimens was compared to that of the Pap test. A cost-effectiveness analysis (CEA) and cost-benefit analysis (CBA) was also performed. RESULTS: The Morelos HPV Study results indicate that HPV testing has a greater sensitivity to detect cervical intraepithelial neoplasia (CIN) 2/3 and CC than the Pap test. Our results also indicate an over-all lower acceptability of the Pap test as compared to the self-collected procedure. The results of the CEA and CBA indicate that screening women between the ages of 20-80 for CC using some type of HPV testing is always more cost-effective than screening for CC using the Pap test. CONCLUSIONS: Our results suggest that self- and clinician-collected HPV testing could be used in CC prevention programs, as an effective complement or substitute for the Pap test.http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0036-36342003000900013cervical cancerscreeningHPV testingPap
spellingShingle Flores Yvonne
Bishai David
Lazcano Eduardo
Shah Keerti
Lörincz Attila
Hernández Mauricio
Salmerón Jorge
Ferris Daron
Hernández Pilar
Sherman Mark E
Ronnett Brigitte M
Carmona Enrique
Antúnez Alfredo
Manzanares Horacio
Uribe Mario
Pérez-Cuevas Ricardo
Leyva Ahideé
Yunes Elsa
Improving cervical cancer screening in Mexico: results from the Morelos HPV Study
Salud Pública de México
cervical cancer
screening
HPV testing
Pap
title Improving cervical cancer screening in Mexico: results from the Morelos HPV Study
title_full Improving cervical cancer screening in Mexico: results from the Morelos HPV Study
title_fullStr Improving cervical cancer screening in Mexico: results from the Morelos HPV Study
title_full_unstemmed Improving cervical cancer screening in Mexico: results from the Morelos HPV Study
title_short Improving cervical cancer screening in Mexico: results from the Morelos HPV Study
title_sort improving cervical cancer screening in mexico results from the morelos hpv study
topic cervical cancer
screening
HPV testing
Pap
url http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0036-36342003000900013
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