Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration with Fine-Needle Biopsy for Solid Gastrointestinal Lesions: A Randomized Crossover Single-Center study
Background/Aims The purpose of this study was to compare the results of endoscopic ultrasound guided fine-needle aspiration (EUS-FNA) and fine-needle biopsy (FNB) performed at the same site in a single session in the same patient. Methods Consecutive patients with solid gastrointestinal l...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2023-03-01
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| Series: | Journal of Digestive Endoscopy |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1760276 |
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| author | Shivaraj Afzalpurkar Vijay Kumar Rai Nikhil Sonthalia Gajanan Rodge Awanesh Tewary Mahesh Goenka |
| author_facet | Shivaraj Afzalpurkar Vijay Kumar Rai Nikhil Sonthalia Gajanan Rodge Awanesh Tewary Mahesh Goenka |
| author_sort | Shivaraj Afzalpurkar |
| collection | DOAJ |
| description | Background/Aims The purpose of this study was to compare the results of endoscopic ultrasound guided fine-needle aspiration (EUS-FNA) and fine-needle biopsy (FNB) performed at the same site in a single session in the same patient.
Methods Consecutive patients with solid gastrointestinal lesions referred for EUS evaluation underwent EUS-FNA and FNB using 22G needles with three and two passes, respectively, in the same session. Patients were randomized to one group having EUS-FNA first followed by EUS-FNB, while other group had EUS-FNB first followed by EUS-FNA.
Results Total 50 patients (31 male) of mean age 56.58 ± 14.2 years and mean lesion size of 2.6 (±2) cm were included. The Kappa agreement for final diagnosis for FNA and FNB was 0.841 and 0.61, respectively. The sensitivity and specificity of FNA versus FNB were 85.19 versus 62.96% and 100 versus 100%, respectively, in comparison with final diagnosis.
Conclusion Both EUS-FNA and FNB are equally safe when compared between the two techniques simultaneously in same lesion. EUS-FNA is better than FNB in terms of sensitivity, diagnostic accuracy, and tissue yield for solid GI lesion. However, the specificity and positive predictive value were equally good for both the modalities. |
| first_indexed | 2024-04-09T20:41:26Z |
| format | Article |
| id | doaj.art-abfc2c6dc0214acab13a031beaf02efe |
| institution | Directory Open Access Journal |
| issn | 0976-5042 0976-5050 |
| language | English |
| last_indexed | 2024-04-09T20:41:26Z |
| publishDate | 2023-03-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Journal of Digestive Endoscopy |
| spelling | doaj.art-abfc2c6dc0214acab13a031beaf02efe2023-03-30T00:12:48ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Digestive Endoscopy0976-50420976-50502023-03-01140101402110.1055/s-0042-1760276Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration with Fine-Needle Biopsy for Solid Gastrointestinal Lesions: A Randomized Crossover Single-Center studyShivaraj Afzalpurkar0Vijay Kumar Rai1Nikhil Sonthalia2Gajanan Rodge3Awanesh Tewary4Mahesh Goenka5Institute of Gastrosciences and Liver, Apollo Multispeciality Hospitals, Kolkata, West Bengal, IndiaInstitute of Gastrosciences and Liver, Apollo Multispeciality Hospitals, Kolkata, West Bengal, IndiaInstitute of Gastrosciences and Liver, Apollo Multispeciality Hospitals, Kolkata, West Bengal, IndiaInstitute of Gastrosciences and Liver, Apollo Multispeciality Hospitals, Kolkata, West Bengal, IndiaInstitute of Gastrosciences and Liver, Apollo Multispeciality Hospitals, Kolkata, West Bengal, IndiaInstitute of Gastrosciences and Liver, Apollo Multispeciality Hospitals, Kolkata, West Bengal, IndiaBackground/Aims The purpose of this study was to compare the results of endoscopic ultrasound guided fine-needle aspiration (EUS-FNA) and fine-needle biopsy (FNB) performed at the same site in a single session in the same patient. Methods Consecutive patients with solid gastrointestinal lesions referred for EUS evaluation underwent EUS-FNA and FNB using 22G needles with three and two passes, respectively, in the same session. Patients were randomized to one group having EUS-FNA first followed by EUS-FNB, while other group had EUS-FNB first followed by EUS-FNA. Results Total 50 patients (31 male) of mean age 56.58 ± 14.2 years and mean lesion size of 2.6 (±2) cm were included. The Kappa agreement for final diagnosis for FNA and FNB was 0.841 and 0.61, respectively. The sensitivity and specificity of FNA versus FNB were 85.19 versus 62.96% and 100 versus 100%, respectively, in comparison with final diagnosis. Conclusion Both EUS-FNA and FNB are equally safe when compared between the two techniques simultaneously in same lesion. EUS-FNA is better than FNB in terms of sensitivity, diagnostic accuracy, and tissue yield for solid GI lesion. However, the specificity and positive predictive value were equally good for both the modalities.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1760276endoscopic ultrasoundfine-needle aspirationfine-needle biopsy |
| spellingShingle | Shivaraj Afzalpurkar Vijay Kumar Rai Nikhil Sonthalia Gajanan Rodge Awanesh Tewary Mahesh Goenka Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration with Fine-Needle Biopsy for Solid Gastrointestinal Lesions: A Randomized Crossover Single-Center study Journal of Digestive Endoscopy endoscopic ultrasound fine-needle aspiration fine-needle biopsy |
| title | Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration with Fine-Needle Biopsy for Solid Gastrointestinal Lesions: A Randomized Crossover Single-Center study |
| title_full | Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration with Fine-Needle Biopsy for Solid Gastrointestinal Lesions: A Randomized Crossover Single-Center study |
| title_fullStr | Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration with Fine-Needle Biopsy for Solid Gastrointestinal Lesions: A Randomized Crossover Single-Center study |
| title_full_unstemmed | Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration with Fine-Needle Biopsy for Solid Gastrointestinal Lesions: A Randomized Crossover Single-Center study |
| title_short | Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration with Fine-Needle Biopsy for Solid Gastrointestinal Lesions: A Randomized Crossover Single-Center study |
| title_sort | comparison of endoscopic ultrasound guided fine needle aspiration with fine needle biopsy for solid gastrointestinal lesions a randomized crossover single center study |
| topic | endoscopic ultrasound fine-needle aspiration fine-needle biopsy |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1760276 |
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