Novel Pathogenic Variants Leading to Sporadic Amyotrophic Lateral Sclerosis in Greek Patients

Novel Pathogenic Variants Leading to Sporadic Amyotrophic Lateral Sclerosis in Greek Patients

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive disease that affects motor neurons, leading to paralysis and death usually 3–5 years after the onset of symptoms. The investigation of both sporadic and familial ALS highlighted four main genes that contribute to the pathogenesis of the di...

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Bibliographic Details
Main Authors: Ouliana Ivantsik, Anne John, Kyriaki Kydonopoulou, Konstantinos Mitropoulos, Spyridon Gerou, Bassam R. Ali, George P. Patrinos
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Genes
Subjects:
amyotrophic lateral sclerosis
sporadic ALS
genetics
<i>SOD1</i>
<i>FUS</i>
<i>TARDBP</i>
Online Access:https://www.mdpi.com/2073-4425/15/3/309

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