Complementary Approaches to Retinal Health Focusing on Diabetic Retinopathy
Diabetes mellitus affects carbohydrate homeostasis but also influences fat and protein metabolism. Due to ophthalmic complications, it is a leading cause of blindness worldwide. The molecular pathology reveals that nuclear factor kappa B (NFκB) has a central role in the progression of diabetic retin...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-11-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/12/23/2699 |
| _version_ | 1797400338364366848 |
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| author | Tibor Rák Andrea Kovács-Valasek Etelka Pöstyéni Adrienne Csutak Róbert Gábriel |
| author_facet | Tibor Rák Andrea Kovács-Valasek Etelka Pöstyéni Adrienne Csutak Róbert Gábriel |
| author_sort | Tibor Rák |
| collection | DOAJ |
| description | Diabetes mellitus affects carbohydrate homeostasis but also influences fat and protein metabolism. Due to ophthalmic complications, it is a leading cause of blindness worldwide. The molecular pathology reveals that nuclear factor kappa B (NFκB) has a central role in the progression of diabetic retinopathy, sharing this signaling pathway with another major retinal disorder, glaucoma. Therefore, new therapeutic approaches can be elaborated to decelerate the ever-emerging “epidemics” of diabetic retinopathy and glaucoma targeting this critical node. In our review, we emphasize the role of an improvement of lifestyle in its prevention as well as the use of phytomedicals associated with evidence-based protocols. A balanced personalized therapy requires an integrative approach to be more successful for prevention and early treatment. |
| first_indexed | 2024-03-09T01:54:05Z |
| format | Article |
| id | doaj.art-abfd1d852f81479e8283b8d21f215e8d |
| institution | Directory Open Access Journal |
| issn | 2073-4409 |
| language | English |
| last_indexed | 2024-03-09T01:54:05Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj.art-abfd1d852f81479e8283b8d21f215e8d2023-12-08T15:13:05ZengMDPI AGCells2073-44092023-11-011223269910.3390/cells12232699Complementary Approaches to Retinal Health Focusing on Diabetic RetinopathyTibor Rák0Andrea Kovács-Valasek1Etelka Pöstyéni2Adrienne Csutak3Róbert Gábriel4Department of Ophthalmology, Clinical Centre, Medical School, University of Pécs, Rákóczi út 2., 7623 Pécs, HungaryDepartment of Neurobiology, University of Pécs, Ifjúság útja 6, 7624 Pécs, HungaryDepartment of Neurobiology, University of Pécs, Ifjúság útja 6, 7624 Pécs, HungaryDepartment of Ophthalmology, Clinical Centre, Medical School, University of Pécs, Rákóczi út 2., 7623 Pécs, HungaryDepartment of Neurobiology, University of Pécs, Ifjúság útja 6, 7624 Pécs, HungaryDiabetes mellitus affects carbohydrate homeostasis but also influences fat and protein metabolism. Due to ophthalmic complications, it is a leading cause of blindness worldwide. The molecular pathology reveals that nuclear factor kappa B (NFκB) has a central role in the progression of diabetic retinopathy, sharing this signaling pathway with another major retinal disorder, glaucoma. Therefore, new therapeutic approaches can be elaborated to decelerate the ever-emerging “epidemics” of diabetic retinopathy and glaucoma targeting this critical node. In our review, we emphasize the role of an improvement of lifestyle in its prevention as well as the use of phytomedicals associated with evidence-based protocols. A balanced personalized therapy requires an integrative approach to be more successful for prevention and early treatment.https://www.mdpi.com/2073-4409/12/23/2699diabetic retinopathyNFκBcomplementary and alternative medicines |
| spellingShingle | Tibor Rák Andrea Kovács-Valasek Etelka Pöstyéni Adrienne Csutak Róbert Gábriel Complementary Approaches to Retinal Health Focusing on Diabetic Retinopathy Cells diabetic retinopathy NFκB complementary and alternative medicines |
| title | Complementary Approaches to Retinal Health Focusing on Diabetic Retinopathy |
| title_full | Complementary Approaches to Retinal Health Focusing on Diabetic Retinopathy |
| title_fullStr | Complementary Approaches to Retinal Health Focusing on Diabetic Retinopathy |
| title_full_unstemmed | Complementary Approaches to Retinal Health Focusing on Diabetic Retinopathy |
| title_short | Complementary Approaches to Retinal Health Focusing on Diabetic Retinopathy |
| title_sort | complementary approaches to retinal health focusing on diabetic retinopathy |
| topic | diabetic retinopathy NFκB complementary and alternative medicines |
| url | https://www.mdpi.com/2073-4409/12/23/2699 |
| work_keys_str_mv | AT tiborrak complementaryapproachestoretinalhealthfocusingondiabeticretinopathy AT andreakovacsvalasek complementaryapproachestoretinalhealthfocusingondiabeticretinopathy AT etelkapostyeni complementaryapproachestoretinalhealthfocusingondiabeticretinopathy AT adriennecsutak complementaryapproachestoretinalhealthfocusingondiabeticretinopathy AT robertgabriel complementaryapproachestoretinalhealthfocusingondiabeticretinopathy |