In vivo imaging of mammary epithelial cell dynamics in response to lineage-biased Wnt/β-catenin activation

In vivo imaging of mammary epithelial cell dynamics in response to lineage-biased Wnt/β-catenin activation

Summary: Real-time in vivo imaging provides an essential window into the spatiotemporal cellular events contributing to tissue development and pathology. By coupling longitudinal intravital imaging with genetic lineage tracing, here we capture the earliest cellular events arising in response to acti...

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Bibliographic Details
Main Authors: Bethan Lloyd-Lewis, Francesca Gobbo, Meghan Perkins, Guillaume Jacquemin, Mathilde Huyghe, Marisa M. Faraldo, Silvia Fre
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Cell Reports
Subjects:
mammary gland development
lineage tracing
β-catenin
Wnt signaling
intravital imaging
in vivo imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722001887

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