GLUT1 targeting and hypoxia-activating polymer-drug conjugate-based micelle for tumor chemo-thermal therapy

GLUT1 targeting and hypoxia-activating polymer-drug conjugate-based micelle for tumor chemo-thermal therapy

Purpose Mitochondria are closely correlated with the proliferation and metastasis of tumor for providing suitable micro-environment and energy supply. Herein, we construct a glucose transporter 1 (GLUT1) targeting and hypoxia activating polyprodrug-based micelle (Glu-PEG-Azo-IR808-S-S-PTX) for mitoc...

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Bibliographic Details
Main Authors: Pengkai Ma, Guijie Wei, Jianhua Chen, Ziqi Jing, Xue Wang, Zhijun Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Drug Delivery
Subjects:
polyprodrug
micelle
mitochondria targeting
tumor microenvironment
chemo-thermal therapy
Online Access:http://dx.doi.org/10.1080/10717544.2021.1992039

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