Sinularin Induces Oxidative Stress-Mediated Apoptosis and Mitochondrial Dysfunction, and Inhibits Angiogenesis in Glioblastoma Cells

Sinularin Induces Oxidative Stress-Mediated Apoptosis and Mitochondrial Dysfunction, and Inhibits Angiogenesis in Glioblastoma Cells

Glioblastoma multiforme (GBM) is a cancer of largely unknown cause that leads to a 5-year survival rate of approximately 7% in the United States. Current treatment strategies are not effective, indicating a strong need for the development of novel therapies. In this study, the outcomes of sinularin,...

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Bibliographic Details
Main Authors: Shih-Yuan Hsu, Zhi-Hong Wen, Po-Chang Shih, Hsiao-Mei Kuo, Sung-Chun Lin, Hsin-Tzu Liu, Yi-Hsin Lee, Yi-Jen Wang, Wu-Fu Chen, Nan-Fu Chen
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Antioxidants
Subjects:
GBM
oxidative stress
mitochondrial dysfunction
angiogenesis
zebrafish
natural product
Online Access:https://www.mdpi.com/2076-3921/11/8/1433

Internet

https://www.mdpi.com/2076-3921/11/8/1433

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