Cognitive-perceptual deficits and symptom correlates in first-episode schizophrenia
Background: Thought disorder and visual-perceptual deficits have been well documented, but their relationships with clinical symptoms and cognitive function remain unclear. Cognitive-perceptual deficits may underscore clinical symptoms in schizophrenia patients. Aim: This study aimed to explore how...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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AOSIS
2017-08-01
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| Series: | South African Journal of Psychiatry |
| Online Access: | https://sajp.org.za/index.php/sajp/article/view/1049 |
| _version_ | 1817978491990179840 |
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| author | Riaan M. Olivier Sanja Kilian Bonginkosi Chiliza Laila Asmal Petrus P. Oosthuizen Robin Emsley Martin Kidd |
| author_facet | Riaan M. Olivier Sanja Kilian Bonginkosi Chiliza Laila Asmal Petrus P. Oosthuizen Robin Emsley Martin Kidd |
| author_sort | Riaan M. Olivier |
| collection | DOAJ |
| description | Background: Thought disorder and visual-perceptual deficits have been well documented, but their relationships with clinical symptoms and cognitive function remain unclear. Cognitive-perceptual deficits may underscore clinical symptoms in schizophrenia patients.
Aim: This study aimed to explore how thought disorder and form perception are related with clinical symptoms and cognitive dysfunction in first-episode schizophrenia.
Setting: Forty-two patients with a first-episode of schizophrenia, schizophreniform or schizoaffective disorder were recruited from community clinics and state hospitals in the Cape Town area.
Methods: Patients were assessed at baseline with the Rorschach Perceptual Thinking Index (PTI), the Positive and Negative Syndrome Scale (PANSS) and the MATRICS Cognitive Consensus Battery (MCCB). Spearman correlational analyses were conducted to investigate relationships between PTI scores, PANSS factor analysis-derived domain scores and MCCB composite and subscale scores. Multiple regression models explored these relationships further.
Results: Unexpectedly, poor form perception (X- %) was inversely correlated with the severity of PANSS positive symptoms (r = -0.42, p = 0.02). Good form perception (XA%) correlated significantly with speed of processing (r = 0.59, p < 0.01), working memory (r = 0.48, p < 0.01) and visual learning (r = 0.55, p < 0.01). PTI measures of thought disorder did not correlate significantly with PANSS symptom scores or cognitive performance.
Conclusions: Form perception is associated with positive symptoms and impairment in executive function during acute psychosis. These findings suggest that there may be clinical value in including sensory-perceptual processing tasks in cognitive remediation and social cognitive training programmes for schizophrenia patients. |
| first_indexed | 2024-04-13T22:30:55Z |
| format | Article |
| id | doaj.art-ac00ef0f4ddc45b0b5b26be4879be531 |
| institution | Directory Open Access Journal |
| issn | 1608-9685 2078-6786 |
| language | English |
| last_indexed | 2024-04-13T22:30:55Z |
| publishDate | 2017-08-01 |
| publisher | AOSIS |
| record_format | Article |
| series | South African Journal of Psychiatry |
| spelling | doaj.art-ac00ef0f4ddc45b0b5b26be4879be5312022-12-22T02:26:56ZengAOSISSouth African Journal of Psychiatry1608-96852078-67862017-08-0123010.4102/sajpsychiatry.v23i0.1049383Cognitive-perceptual deficits and symptom correlates in first-episode schizophreniaRiaan M. Olivier0Sanja Kilian1Bonginkosi Chiliza2Laila Asmal3Petrus P. Oosthuizen4Robin Emsley5Martin Kidd6Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch UniversityDepartment of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch UniversityDepartment of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch UniversityDepartment of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch UniversityDepartment of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch UniversityDepartment of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch UniversityDepartment of Statistics and Actuarial Sciences, Stellenbosch UniversityBackground: Thought disorder and visual-perceptual deficits have been well documented, but their relationships with clinical symptoms and cognitive function remain unclear. Cognitive-perceptual deficits may underscore clinical symptoms in schizophrenia patients. Aim: This study aimed to explore how thought disorder and form perception are related with clinical symptoms and cognitive dysfunction in first-episode schizophrenia. Setting: Forty-two patients with a first-episode of schizophrenia, schizophreniform or schizoaffective disorder were recruited from community clinics and state hospitals in the Cape Town area. Methods: Patients were assessed at baseline with the Rorschach Perceptual Thinking Index (PTI), the Positive and Negative Syndrome Scale (PANSS) and the MATRICS Cognitive Consensus Battery (MCCB). Spearman correlational analyses were conducted to investigate relationships between PTI scores, PANSS factor analysis-derived domain scores and MCCB composite and subscale scores. Multiple regression models explored these relationships further. Results: Unexpectedly, poor form perception (X- %) was inversely correlated with the severity of PANSS positive symptoms (r = -0.42, p = 0.02). Good form perception (XA%) correlated significantly with speed of processing (r = 0.59, p < 0.01), working memory (r = 0.48, p < 0.01) and visual learning (r = 0.55, p < 0.01). PTI measures of thought disorder did not correlate significantly with PANSS symptom scores or cognitive performance. Conclusions: Form perception is associated with positive symptoms and impairment in executive function during acute psychosis. These findings suggest that there may be clinical value in including sensory-perceptual processing tasks in cognitive remediation and social cognitive training programmes for schizophrenia patients.https://sajp.org.za/index.php/sajp/article/view/1049 |
| spellingShingle | Riaan M. Olivier Sanja Kilian Bonginkosi Chiliza Laila Asmal Petrus P. Oosthuizen Robin Emsley Martin Kidd Cognitive-perceptual deficits and symptom correlates in first-episode schizophrenia South African Journal of Psychiatry |
| title | Cognitive-perceptual deficits and symptom correlates in first-episode schizophrenia |
| title_full | Cognitive-perceptual deficits and symptom correlates in first-episode schizophrenia |
| title_fullStr | Cognitive-perceptual deficits and symptom correlates in first-episode schizophrenia |
| title_full_unstemmed | Cognitive-perceptual deficits and symptom correlates in first-episode schizophrenia |
| title_short | Cognitive-perceptual deficits and symptom correlates in first-episode schizophrenia |
| title_sort | cognitive perceptual deficits and symptom correlates in first episode schizophrenia |
| url | https://sajp.org.za/index.php/sajp/article/view/1049 |
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