MicroRNA therapeutics: Discovering novel targets and developing specific therapy
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression in diverse biological process. They act as intracellular mediators that are necessary for various biological processes. MicroRNAs targeting pathways of human disease provide a new and potential powerful candidate for...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Perspectives in Clinical Research |
| Subjects: | |
| Online Access: | http://www.picronline.org/article.asp?issn=2229-3485;year=2016;volume=7;issue=2;spage=68;epage=74;aulast=Christopher |
| _version_ | 1828529790969184256 |
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| author | Ajay Francis Christopher Raman Preet Kaur Gunpreet Kaur Amandeep Kaur Vikas Gupta Parveen Bansal |
| author_facet | Ajay Francis Christopher Raman Preet Kaur Gunpreet Kaur Amandeep Kaur Vikas Gupta Parveen Bansal |
| author_sort | Ajay Francis Christopher |
| collection | DOAJ |
| description | MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression in diverse biological process. They act as intracellular mediators that are necessary for various biological processes. MicroRNAs targeting pathways of human disease provide a new and potential powerful candidate for therapeutic intervention against various pathological conditions. Even though, the information about miRNA biology has significantly enriched but we still do not completely understand the mechanism of miRNA gene regulation. Various groups across the globe and pharmaceutical companies are conducting research and developments to explore miRNA based therapy and build a whole new area of miroRNA therapeutics. Consequently, few miRNAs have entered the preclinical and clinical stage and soon might be available in the market for use in humans. |
| first_indexed | 2024-12-11T22:13:57Z |
| format | Article |
| id | doaj.art-ac013f8e2f1846d19069096181d37c0c |
| institution | Directory Open Access Journal |
| issn | 2229-3485 |
| language | English |
| last_indexed | 2024-12-11T22:13:57Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Perspectives in Clinical Research |
| spelling | doaj.art-ac013f8e2f1846d19069096181d37c0c2022-12-22T00:48:41ZengWolters Kluwer Medknow PublicationsPerspectives in Clinical Research2229-34852016-01-0172687410.4103/2229-3485.179431MicroRNA therapeutics: Discovering novel targets and developing specific therapyAjay Francis ChristopherRaman Preet KaurGunpreet KaurAmandeep KaurVikas GuptaParveen BansalMicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression in diverse biological process. They act as intracellular mediators that are necessary for various biological processes. MicroRNAs targeting pathways of human disease provide a new and potential powerful candidate for therapeutic intervention against various pathological conditions. Even though, the information about miRNA biology has significantly enriched but we still do not completely understand the mechanism of miRNA gene regulation. Various groups across the globe and pharmaceutical companies are conducting research and developments to explore miRNA based therapy and build a whole new area of miroRNA therapeutics. Consequently, few miRNAs have entered the preclinical and clinical stage and soon might be available in the market for use in humans.http://www.picronline.org/article.asp?issn=2229-3485;year=2016;volume=7;issue=2;spage=68;epage=74;aulast=ChristopherClinical stagegene expressionmicroRNAtherapeutics |
| spellingShingle | Ajay Francis Christopher Raman Preet Kaur Gunpreet Kaur Amandeep Kaur Vikas Gupta Parveen Bansal MicroRNA therapeutics: Discovering novel targets and developing specific therapy Perspectives in Clinical Research Clinical stage gene expression microRNA therapeutics |
| title | MicroRNA therapeutics: Discovering novel targets and developing specific therapy |
| title_full | MicroRNA therapeutics: Discovering novel targets and developing specific therapy |
| title_fullStr | MicroRNA therapeutics: Discovering novel targets and developing specific therapy |
| title_full_unstemmed | MicroRNA therapeutics: Discovering novel targets and developing specific therapy |
| title_short | MicroRNA therapeutics: Discovering novel targets and developing specific therapy |
| title_sort | microrna therapeutics discovering novel targets and developing specific therapy |
| topic | Clinical stage gene expression microRNA therapeutics |
| url | http://www.picronline.org/article.asp?issn=2229-3485;year=2016;volume=7;issue=2;spage=68;epage=74;aulast=Christopher |
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