Histological evaluation of nerve sparing technique in robotic assisted radical prostatectomy
Introduction: The objective of this study is to compare intrafascial nerve-sparing (NS), interfascial NS and non-NS prostatecomy specimens to assess the feasibility of NS technique in Robot-assisted radical prostatectomies (RARP). Materials and Methods: The records of the first 43 consecutive patie...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Indian Journal of Urology |
| Subjects: | |
| Online Access: | http://www.indianjurol.com/article.asp?issn=0970-1591;year=2014;volume=30;issue=3;spage=268;epage=272;aulast=Tanaka |
| _version_ | 1818277079710433280 |
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| author | Kazushi Tanaka Katsumi Shigemura Nobuyuki Hinata Mototsugu Muramaki Hideaki Miyake Masato Fujisawa |
| author_facet | Kazushi Tanaka Katsumi Shigemura Nobuyuki Hinata Mototsugu Muramaki Hideaki Miyake Masato Fujisawa |
| author_sort | Kazushi Tanaka |
| collection | DOAJ |
| description | Introduction: The objective of this study is to compare intrafascial nerve-sparing (NS), interfascial NS and non-NS prostatecomy specimens to assess the feasibility of NS technique in Robot-assisted radical prostatectomies (RARP).
Materials and Methods: The records of the first 43 consecutive patients (86 prostatic sides (lobe) who underwent NS RARP (6 intrafascial NS, 46 interfacial NS, 34 non-NS) were reviewed and histopathological examinations were performed. The presence and distribution of periprostatic neurovascular structures were histologically evaluated using mid-gland section of each prostate lobe in the prostatectomy specimen and it was immunostained with the S-100 antibody for quantitative analysis of nerves.
Results: The average number of nerve fibers per prostatic half was 37.2 ± 20.6. The number of resected peri-prostatic nerves counted was 13.7 ± 13.5, 30.5 ± 15.0 and 50.4 ± 20.4 in intrafascial NS, interfascial NS and non-NS specimens, respectively. The difference in the number of nerve bundle counts in the three groups was statistically significant (P < 0.05). Patients with urinary continence at 6 months after surgery had significantly less number of nerve fibers resected with the prostate than the incontinence group (P = 0.013) and the number of nerve fi bers resected in the potent group were lower than in the impotent group but did not reach statistical significance (P = 0.057).
Conclusions: Our study showed that NS RARP could be performed according to surgeons′ intention (intrafascial, interfascial or non-NS) and urinary continence significantly correlated to the number of nerve fibers resected with the prostate. |
| first_indexed | 2024-12-12T22:55:51Z |
| format | Article |
| id | doaj.art-ac01d14135594496bd67d91c69e52fbd |
| institution | Directory Open Access Journal |
| issn | 0970-1591 1998-3824 |
| language | English |
| last_indexed | 2024-12-12T22:55:51Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Urology |
| spelling | doaj.art-ac01d14135594496bd67d91c69e52fbd2022-12-22T00:08:56ZengWolters Kluwer Medknow PublicationsIndian Journal of Urology0970-15911998-38242014-01-0130326827210.4103/0970-1591.128500Histological evaluation of nerve sparing technique in robotic assisted radical prostatectomyKazushi TanakaKatsumi ShigemuraNobuyuki HinataMototsugu MuramakiHideaki MiyakeMasato FujisawaIntroduction: The objective of this study is to compare intrafascial nerve-sparing (NS), interfascial NS and non-NS prostatecomy specimens to assess the feasibility of NS technique in Robot-assisted radical prostatectomies (RARP). Materials and Methods: The records of the first 43 consecutive patients (86 prostatic sides (lobe) who underwent NS RARP (6 intrafascial NS, 46 interfacial NS, 34 non-NS) were reviewed and histopathological examinations were performed. The presence and distribution of periprostatic neurovascular structures were histologically evaluated using mid-gland section of each prostate lobe in the prostatectomy specimen and it was immunostained with the S-100 antibody for quantitative analysis of nerves. Results: The average number of nerve fibers per prostatic half was 37.2 ± 20.6. The number of resected peri-prostatic nerves counted was 13.7 ± 13.5, 30.5 ± 15.0 and 50.4 ± 20.4 in intrafascial NS, interfascial NS and non-NS specimens, respectively. The difference in the number of nerve bundle counts in the three groups was statistically significant (P < 0.05). Patients with urinary continence at 6 months after surgery had significantly less number of nerve fibers resected with the prostate than the incontinence group (P = 0.013) and the number of nerve fi bers resected in the potent group were lower than in the impotent group but did not reach statistical significance (P = 0.057). Conclusions: Our study showed that NS RARP could be performed according to surgeons′ intention (intrafascial, interfascial or non-NS) and urinary continence significantly correlated to the number of nerve fibers resected with the prostate.http://www.indianjurol.com/article.asp?issn=0970-1591;year=2014;volume=30;issue=3;spage=268;epage=272;aulast=TanakaHistological evaluationnerve-sparingrobot-assisted radical prostatectomy |
| spellingShingle | Kazushi Tanaka Katsumi Shigemura Nobuyuki Hinata Mototsugu Muramaki Hideaki Miyake Masato Fujisawa Histological evaluation of nerve sparing technique in robotic assisted radical prostatectomy Indian Journal of Urology Histological evaluation nerve-sparing robot-assisted radical prostatectomy |
| title | Histological evaluation of nerve sparing technique in robotic assisted radical prostatectomy |
| title_full | Histological evaluation of nerve sparing technique in robotic assisted radical prostatectomy |
| title_fullStr | Histological evaluation of nerve sparing technique in robotic assisted radical prostatectomy |
| title_full_unstemmed | Histological evaluation of nerve sparing technique in robotic assisted radical prostatectomy |
| title_short | Histological evaluation of nerve sparing technique in robotic assisted radical prostatectomy |
| title_sort | histological evaluation of nerve sparing technique in robotic assisted radical prostatectomy |
| topic | Histological evaluation nerve-sparing robot-assisted radical prostatectomy |
| url | http://www.indianjurol.com/article.asp?issn=0970-1591;year=2014;volume=30;issue=3;spage=268;epage=272;aulast=Tanaka |
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