Ca<sup>2+</sup>-Driven Selectivity of the Effect of the Cardiotonic Steroid Marinobufagenin on Rabbit Sinoatrial Node Function

Ca<sup>2+</sup>-Driven Selectivity of the Effect of the Cardiotonic Steroid Marinobufagenin on Rabbit Sinoatrial Node Function

The synergy between Na<sup>+</sup>-K<sup>+</sup> pumps, Na<sup>+</sup>-Ca<sup>2+</sup> exchangers, membrane currents and the sarcoplasmic reticulum (SR) generates the coupled-clock system, which governs the spontaneous electrical activity of heart sino...

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Bibliographic Details
Main Authors: Sofia Segal, Yael Yaniv
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cells
Subjects:
cardiac automaticity
calcium
glycoside
sodium
Online Access:https://www.mdpi.com/2073-4409/12/14/1881

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