B cell overexpression of FCRL5 and PD-1 is associated with low antibody titers in HCV infection.

B cell overexpression of FCRL5 and PD-1 is associated with low antibody titers in HCV infection.

Antibodies targeting the hepatitis C virus (HCV) envelope glycoprotein E2 are associated with delayed disease progression, and these antibodies can also facilitate spontaneous clearance of infection in some individuals. However, many infected people demonstrate low titer and delayed anti-E2 antibody...

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Bibliographic Details
Main Authors: Clinton O Ogega, Nicole E Skinner, Andrew I Flyak, Kaitlyn E Clark, Nathan L Board, Pamela J Bjorkman, James E Crowe, Andrea L Cox, Stuart C Ray, Justin R Bailey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010179

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