The DarT/DarG Toxin–Antitoxin ADP-Ribosylation System as a Novel Target for a Rational Design of Innovative Antimicrobial Strategies

The DarT/DarG Toxin–Antitoxin ADP-Ribosylation System as a Novel Target for a Rational Design of Innovative Antimicrobial Strategies

The chemical modification of cellular macromolecules by the transfer of ADP-ribose unit(s), known as ADP-ribosylation, is an ancient homeostatic and stress response control system. Highly conserved across the evolution, ADP-ribosyltransferases and ADP-ribosylhydrolases control ADP-ribosylation signa...

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Bibliographic Details
Main Authors:	Giuliana Catara, Rocco Caggiano, Luca Palazzo
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Series:	Pathogens
Subjects:	ADP-ribosylation toxin–antitoxin DarT/DarG DNA modification cell growth phage defence
Online Access:	https://www.mdpi.com/2076-0817/12/2/240

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