Cutaneous Crohn disease without intestinal manifestations
Extraintestinal manifestations (EIMs) are common in patients with Crohn's disease (CD). Various reactive cutaneous conditions, including erythema nodosum and pyoderma gangrenosum frequently occur as a part of EIMs. However, cutaneous metastasis of CD is rarely encountered in CD patients. Here,...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Advanced Biomedical Research |
| Subjects: | |
| Online Access: | http://www.advbiores.net/article.asp?issn=2277-9175;year=2021;volume=10;issue=1;spage=39;epage=39;aulast=Vahabi-Amlashi |
| _version_ | 1818845467367178240 |
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| author | Sadegh Vahabi-Amlashi Sara Molkara Yahya Shahrokhi |
| author_facet | Sadegh Vahabi-Amlashi Sara Molkara Yahya Shahrokhi |
| author_sort | Sadegh Vahabi-Amlashi |
| collection | DOAJ |
| description | Extraintestinal manifestations (EIMs) are common in patients with Crohn's disease (CD). Various reactive cutaneous conditions, including erythema nodosum and pyoderma gangrenosum frequently occur as a part of EIMs. However, cutaneous metastasis of CD is rarely encountered in CD patients. Here, we report a 28-year-old female patient presenting with discharging deep fissures on genital and intergluteal regions. The result of a skin biopsy showed noncaseating granulomas. After rule out all the other differential diagnoses for granulomatous skin lesions, we believe this patient may be a case of CD, presenting with skin metastasis and GI tract involvement has not been occurred during 1-year follow-up. We suggest including cutaneous (metastatic) CD in the list of dermatologic differential diagnoses for cutaneous lesions of these sites. These lesions can occasionally precede gastrointestinal (GI) involvement by months and years, therefore, an appropriate follow-up needs to be done to detect GI lesions as soon as they appear. |
| first_indexed | 2024-12-19T05:30:07Z |
| format | Article |
| id | doaj.art-ac093e93655e4da49907b6c66ac91eda |
| institution | Directory Open Access Journal |
| issn | 2277-9175 |
| language | English |
| last_indexed | 2024-12-19T05:30:07Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Advanced Biomedical Research |
| spelling | doaj.art-ac093e93655e4da49907b6c66ac91eda2022-12-21T20:34:16ZengWolters Kluwer Medknow PublicationsAdvanced Biomedical Research2277-91752021-01-01101393910.4103/abr.abr_180_19Cutaneous Crohn disease without intestinal manifestationsSadegh Vahabi-AmlashiSara MolkaraYahya ShahrokhiExtraintestinal manifestations (EIMs) are common in patients with Crohn's disease (CD). Various reactive cutaneous conditions, including erythema nodosum and pyoderma gangrenosum frequently occur as a part of EIMs. However, cutaneous metastasis of CD is rarely encountered in CD patients. Here, we report a 28-year-old female patient presenting with discharging deep fissures on genital and intergluteal regions. The result of a skin biopsy showed noncaseating granulomas. After rule out all the other differential diagnoses for granulomatous skin lesions, we believe this patient may be a case of CD, presenting with skin metastasis and GI tract involvement has not been occurred during 1-year follow-up. We suggest including cutaneous (metastatic) CD in the list of dermatologic differential diagnoses for cutaneous lesions of these sites. These lesions can occasionally precede gastrointestinal (GI) involvement by months and years, therefore, an appropriate follow-up needs to be done to detect GI lesions as soon as they appear.http://www.advbiores.net/article.asp?issn=2277-9175;year=2021;volume=10;issue=1;spage=39;epage=39;aulast=Vahabi-Amlashimetastatic crohn diseasenoncaseating granulomasvulvoperineal fissures |
| spellingShingle | Sadegh Vahabi-Amlashi Sara Molkara Yahya Shahrokhi Cutaneous Crohn disease without intestinal manifestations Advanced Biomedical Research metastatic crohn disease noncaseating granulomas vulvoperineal fissures |
| title | Cutaneous Crohn disease without intestinal manifestations |
| title_full | Cutaneous Crohn disease without intestinal manifestations |
| title_fullStr | Cutaneous Crohn disease without intestinal manifestations |
| title_full_unstemmed | Cutaneous Crohn disease without intestinal manifestations |
| title_short | Cutaneous Crohn disease without intestinal manifestations |
| title_sort | cutaneous crohn disease without intestinal manifestations |
| topic | metastatic crohn disease noncaseating granulomas vulvoperineal fissures |
| url | http://www.advbiores.net/article.asp?issn=2277-9175;year=2021;volume=10;issue=1;spage=39;epage=39;aulast=Vahabi-Amlashi |
| work_keys_str_mv | AT sadeghvahabiamlashi cutaneouscrohndiseasewithoutintestinalmanifestations AT saramolkara cutaneouscrohndiseasewithoutintestinalmanifestations AT yahyashahrokhi cutaneouscrohndiseasewithoutintestinalmanifestations |