Comparison of Diagnostic Values of ACR TI-RADS versus C-TIRADS Scoring and Classification Systems for the Elderly Thyroid Cancers
Hu Huang,1 Ming-Jie Zhu,1 Qi Gao,2 Yan-Li Huang,3 Wei-Min Li4 1Department of Thyroid and Breast Surgery, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, People’s Republic of China; 2Department of Ultrasonography, Southeast University Affiliated Zhongda Hospital, Nanjing, Jiangsu, People’s...
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Dove Medical Press
2023-09-01
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| Series: | International Journal of General Medicine |
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| Online Access: | https://www.dovepress.com/comparison-of-diagnostic-values-of-acr-ti-rads-versus-c-tirads-scoring-peer-reviewed-fulltext-article-IJGM |
| _version_ | 1827802757270077440 |
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| author | Huang H Zhu MJ Gao Q Huang YL Li WM |
| author_facet | Huang H Zhu MJ Gao Q Huang YL Li WM |
| author_sort | Huang H |
| collection | DOAJ |
| description | Hu Huang,1 Ming-Jie Zhu,1 Qi Gao,2 Yan-Li Huang,3 Wei-Min Li4 1Department of Thyroid and Breast Surgery, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, People’s Republic of China; 2Department of Ultrasonography, Southeast University Affiliated Zhongda Hospital, Nanjing, Jiangsu, People’s Republic of China; 3Department of Special Clinic, General Hospital of Eastern Theater Command, PLA, Nanjing, Jiangsu, People’s Republic of China; 4Department of Ultrasonography, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, People’s Republic of ChinaCorrespondence: Wei-Min Li, Department of Ultrasonography, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, 214000, People’s Republic of China, Tel +8613912362309, Email 1005342597@qq.comPurpose: To compare the diagnostic value of the Thyroid Imaging Reporting and Data System (TI-RADS) of the American College of Radiology (ACR) versus the Chinese Thyroid Imaging Reporting and Data System (C-TIRADS) scoring and classification system for elderly thyroid cancers.Patients and Methods: A total of 512 nodules from 465 patients aged ≥ 60 with surgical pathology-proven thyroid nodules were enrolled in our study. The ultrasound features of thyroid nodules were independently evaluated by the ACR TI-RADS and C-TIRADS classification systems, and the receiver operating characteristic curve (ROC) was plotted. The optimal cut-off values of the ACR TI-RADS and C-TIRADS scoring and classification systems for diagnosing elderly thyroid nodules were estimated, and the diagnostic efficacy was analyzed.Results: The ACR TI-RADS and C-TIRADS scores and classifications of thyroid cancers were both higher than benign nodules (both P < 0.05). The area under the curve (AUC) of ACR TI-RADS and C-TIRADS scoring and classification systems were 0.861, 0.897, 0.879, and 0.900, respectively, and the AUC of the scoring system was greater than the classification system for both criteria. When the Youden index was the highest, the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the ACR TI-RADS scoring and classification systems were consistent, ie, they were 89.66%, 41.70%, 89.93%, and 59.00%, respectively; the sensitivity, specificity, PPV, and NPV of the C-TIRADS scoring and classification systems were also consistent, ie, they were 88.71%, 44.26%, 90.23%, 59.69%, respectively. The diagnostic efficacy between the two systems was not statistically significant.Conclusion: ACR TI-RADS and C-TIRADS systems had relatively high diagnostic efficacy for elderly thyroid cancer. The diagnostic efficiency of the scoring systems of ACR TI-RADS and C-TIRADS were higher than the classification systems. In addition, the two systems had high clinical practical values, while there is still a significant risk of missed diagnosis.Keywords: thyroid imaging reporting and data system, ultrasound, thyroid nodules, elderly |
| first_indexed | 2024-03-11T20:44:37Z |
| format | Article |
| id | doaj.art-ac094890893c4970ba37b29358e2c98e |
| institution | Directory Open Access Journal |
| issn | 1178-7074 |
| language | English |
| last_indexed | 2024-03-11T20:44:37Z |
| publishDate | 2023-09-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of General Medicine |
| spelling | doaj.art-ac094890893c4970ba37b29358e2c98e2023-10-01T18:14:19ZengDove Medical PressInternational Journal of General Medicine1178-70742023-09-01Volume 164441445187075Comparison of Diagnostic Values of ACR TI-RADS versus C-TIRADS Scoring and Classification Systems for the Elderly Thyroid CancersHuang HZhu MJGao QHuang YLLi WMHu Huang,1 Ming-Jie Zhu,1 Qi Gao,2 Yan-Li Huang,3 Wei-Min Li4 1Department of Thyroid and Breast Surgery, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, People’s Republic of China; 2Department of Ultrasonography, Southeast University Affiliated Zhongda Hospital, Nanjing, Jiangsu, People’s Republic of China; 3Department of Special Clinic, General Hospital of Eastern Theater Command, PLA, Nanjing, Jiangsu, People’s Republic of China; 4Department of Ultrasonography, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, People’s Republic of ChinaCorrespondence: Wei-Min Li, Department of Ultrasonography, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, 214000, People’s Republic of China, Tel +8613912362309, Email 1005342597@qq.comPurpose: To compare the diagnostic value of the Thyroid Imaging Reporting and Data System (TI-RADS) of the American College of Radiology (ACR) versus the Chinese Thyroid Imaging Reporting and Data System (C-TIRADS) scoring and classification system for elderly thyroid cancers.Patients and Methods: A total of 512 nodules from 465 patients aged ≥ 60 with surgical pathology-proven thyroid nodules were enrolled in our study. The ultrasound features of thyroid nodules were independently evaluated by the ACR TI-RADS and C-TIRADS classification systems, and the receiver operating characteristic curve (ROC) was plotted. The optimal cut-off values of the ACR TI-RADS and C-TIRADS scoring and classification systems for diagnosing elderly thyroid nodules were estimated, and the diagnostic efficacy was analyzed.Results: The ACR TI-RADS and C-TIRADS scores and classifications of thyroid cancers were both higher than benign nodules (both P < 0.05). The area under the curve (AUC) of ACR TI-RADS and C-TIRADS scoring and classification systems were 0.861, 0.897, 0.879, and 0.900, respectively, and the AUC of the scoring system was greater than the classification system for both criteria. When the Youden index was the highest, the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the ACR TI-RADS scoring and classification systems were consistent, ie, they were 89.66%, 41.70%, 89.93%, and 59.00%, respectively; the sensitivity, specificity, PPV, and NPV of the C-TIRADS scoring and classification systems were also consistent, ie, they were 88.71%, 44.26%, 90.23%, 59.69%, respectively. The diagnostic efficacy between the two systems was not statistically significant.Conclusion: ACR TI-RADS and C-TIRADS systems had relatively high diagnostic efficacy for elderly thyroid cancer. The diagnostic efficiency of the scoring systems of ACR TI-RADS and C-TIRADS were higher than the classification systems. In addition, the two systems had high clinical practical values, while there is still a significant risk of missed diagnosis.Keywords: thyroid imaging reporting and data system, ultrasound, thyroid nodules, elderlyhttps://www.dovepress.com/comparison-of-diagnostic-values-of-acr-ti-rads-versus-c-tirads-scoring-peer-reviewed-fulltext-article-IJGMthyroid imaging reporting and data systemultrasoundthyroid noduleselderly |
| spellingShingle | Huang H Zhu MJ Gao Q Huang YL Li WM Comparison of Diagnostic Values of ACR TI-RADS versus C-TIRADS Scoring and Classification Systems for the Elderly Thyroid Cancers International Journal of General Medicine thyroid imaging reporting and data system ultrasound thyroid nodules elderly |
| title | Comparison of Diagnostic Values of ACR TI-RADS versus C-TIRADS Scoring and Classification Systems for the Elderly Thyroid Cancers |
| title_full | Comparison of Diagnostic Values of ACR TI-RADS versus C-TIRADS Scoring and Classification Systems for the Elderly Thyroid Cancers |
| title_fullStr | Comparison of Diagnostic Values of ACR TI-RADS versus C-TIRADS Scoring and Classification Systems for the Elderly Thyroid Cancers |
| title_full_unstemmed | Comparison of Diagnostic Values of ACR TI-RADS versus C-TIRADS Scoring and Classification Systems for the Elderly Thyroid Cancers |
| title_short | Comparison of Diagnostic Values of ACR TI-RADS versus C-TIRADS Scoring and Classification Systems for the Elderly Thyroid Cancers |
| title_sort | comparison of diagnostic values of acr ti rads versus c tirads scoring and classification systems for the elderly thyroid cancers |
| topic | thyroid imaging reporting and data system ultrasound thyroid nodules elderly |
| url | https://www.dovepress.com/comparison-of-diagnostic-values-of-acr-ti-rads-versus-c-tirads-scoring-peer-reviewed-fulltext-article-IJGM |
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