Assessment of efficiency of application of various analogues of insulin in treatment of diabetes type 2
Purpose: to estimate efficiency of treatment of analogues of insulin Glargin and insulin Detemir in patients with diabetes type 2. Material and methods. 147 patients with diabetes type 2 which have been initially receiving combined therapy by oral antihyperglycemic agent and NPH-insulin have been un...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Saratov State Medical University
2014-09-01
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| Series: | Саратовский научно-медицинский журнал |
| Subjects: | |
| Online Access: | http://www.ssmj.ru/system/files/2014_03_461-464.pdf |
| _version_ | 1818893950099914752 |
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| author | Rodionova T.l. Orlova M.M. |
| author_facet | Rodionova T.l. Orlova M.M. |
| author_sort | Rodionova T.l. |
| collection | DOAJ |
| description | Purpose: to estimate efficiency of treatment of analogues of insulin Glargin and insulin Detemir in patients with diabetes type 2. Material and methods. 147 patients with diabetes type 2 which have been initially receiving combined therapy by oral antihyperglycemic agent and NPH-insulin have been under the study. Level of glycated hemoglobin has been defined in 3 and 6 months for the general assessment of control of aglycemia. Results. According to the study the use of insulin analogues (Detemir, Glargin) versus NPH insulin for 6 months allowed to reach individual target values of glycemia in 70% of patients with diabetes type 2 with a low risk of hypoglycemia. Conclusion. The use in clinical practice of modern insulin analogues and simple algorithm for dose titration, allows simulating as closely as possible the physiological insulin secretion, helping to achieve compensation of carbohydrate metabolism in larger numbers of patients in comparison with NPH insulin. |
| first_indexed | 2024-12-19T18:20:44Z |
| format | Article |
| id | doaj.art-ac0a56f7a6de40f3bc8aeec07fefb563 |
| institution | Directory Open Access Journal |
| issn | 2076-2518 |
| language | Russian |
| last_indexed | 2024-12-19T18:20:44Z |
| publishDate | 2014-09-01 |
| publisher | Saratov State Medical University |
| record_format | Article |
| series | Саратовский научно-медицинский журнал |
| spelling | doaj.art-ac0a56f7a6de40f3bc8aeec07fefb5632022-12-21T20:10:59ZrusSaratov State Medical UniversityСаратовский научно-медицинский журнал2076-25182014-09-011034614643770Assessment of efficiency of application of various analogues of insulin in treatment of diabetes type 2Rodionova T.l.0Orlova M.M.1Saratov State Medical UniversitySaratov State Medical UniversityPurpose: to estimate efficiency of treatment of analogues of insulin Glargin and insulin Detemir in patients with diabetes type 2. Material and methods. 147 patients with diabetes type 2 which have been initially receiving combined therapy by oral antihyperglycemic agent and NPH-insulin have been under the study. Level of glycated hemoglobin has been defined in 3 and 6 months for the general assessment of control of aglycemia. Results. According to the study the use of insulin analogues (Detemir, Glargin) versus NPH insulin for 6 months allowed to reach individual target values of glycemia in 70% of patients with diabetes type 2 with a low risk of hypoglycemia. Conclusion. The use in clinical practice of modern insulin analogues and simple algorithm for dose titration, allows simulating as closely as possible the physiological insulin secretion, helping to achieve compensation of carbohydrate metabolism in larger numbers of patients in comparison with NPH insulin.http://www.ssmj.ru/system/files/2014_03_461-464.pdfdiabetes II typeglycemic controlinsulin Detemirinsulin Glargine |
| spellingShingle | Rodionova T.l. Orlova M.M. Assessment of efficiency of application of various analogues of insulin in treatment of diabetes type 2 Саратовский научно-медицинский журнал diabetes II type glycemic control insulin Detemir insulin Glargine |
| title | Assessment of efficiency of application of various analogues of insulin in treatment of diabetes type 2 |
| title_full | Assessment of efficiency of application of various analogues of insulin in treatment of diabetes type 2 |
| title_fullStr | Assessment of efficiency of application of various analogues of insulin in treatment of diabetes type 2 |
| title_full_unstemmed | Assessment of efficiency of application of various analogues of insulin in treatment of diabetes type 2 |
| title_short | Assessment of efficiency of application of various analogues of insulin in treatment of diabetes type 2 |
| title_sort | assessment of efficiency of application of various analogues of insulin in treatment of diabetes type 2 |
| topic | diabetes II type glycemic control insulin Detemir insulin Glargine |
| url | http://www.ssmj.ru/system/files/2014_03_461-464.pdf |
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