Electrically Conductive Materials: Opportunities and Challenges in Tissue Engineering
Tissue engineering endeavors to regenerate tissues and organs through appropriate cellular and molecular interactions at biological interfaces. To this aim, bio-mimicking scaffolds have been designed and practiced to regenerate and repair dysfunctional tissues by modifying cellular activity. Cellula...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-09-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/9/9/448 |
| _version_ | 1828432192168001536 |
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| author | Azadeh Saberi Farzaneh Jabbari Payam Zarrintaj Mohammad Reza Saeb Masoud Mozafari |
| author_facet | Azadeh Saberi Farzaneh Jabbari Payam Zarrintaj Mohammad Reza Saeb Masoud Mozafari |
| author_sort | Azadeh Saberi |
| collection | DOAJ |
| description | Tissue engineering endeavors to regenerate tissues and organs through appropriate cellular and molecular interactions at biological interfaces. To this aim, bio-mimicking scaffolds have been designed and practiced to regenerate and repair dysfunctional tissues by modifying cellular activity. Cellular activity and intracellular signaling are performances given to a tissue as a result of the function of elaborated electrically conductive materials. In some cases, conductive materials have exhibited antibacterial properties; moreover, such materials can be utilized for on-demand drug release. Various types of materials ranging from polymers to ceramics and metals have been utilized as parts of conductive tissue engineering scaffolds, having conductivity assortments from a range of semi-conductive to conductive. The cellular and molecular activity can also be affected by the microstructure; therefore, the fabrication methods should be evaluated along with an appropriate selection of conductive materials. This review aims to address the research progress toward the use of electrically conductive materials for the modulation of cellular response at the material-tissue interface for tissue engineering applications. |
| first_indexed | 2024-12-10T18:16:34Z |
| format | Article |
| id | doaj.art-ac0d0c372dc9448bb5f7c434f977e750 |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-12-10T18:16:34Z |
| publishDate | 2019-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-ac0d0c372dc9448bb5f7c434f977e7502022-12-22T01:38:19ZengMDPI AGBiomolecules2218-273X2019-09-019944810.3390/biom9090448biom9090448Electrically Conductive Materials: Opportunities and Challenges in Tissue EngineeringAzadeh Saberi0Farzaneh Jabbari1Payam Zarrintaj2Mohammad Reza Saeb3Masoud Mozafari4Nanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), P.O. Box: 31787-316 Tehran, IranNanotechnology and Advanced Materials Department, Materials and Energy Research Center (MERC), P.O. Box: 31787-316 Tehran, IranPolymer Engineering Department, Faculty of Engineering, Urmia University, P.O. Box: 5756151818-165 Urmia, IranDepartment of Resin and Additives, Institute for Color Science and Technology, P.O. Box: 16765-654 Tehran, IranDepartment of Tissue Engineering & Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences (IUMS), P.O Box: 14665-354 Tehran, IranTissue engineering endeavors to regenerate tissues and organs through appropriate cellular and molecular interactions at biological interfaces. To this aim, bio-mimicking scaffolds have been designed and practiced to regenerate and repair dysfunctional tissues by modifying cellular activity. Cellular activity and intracellular signaling are performances given to a tissue as a result of the function of elaborated electrically conductive materials. In some cases, conductive materials have exhibited antibacterial properties; moreover, such materials can be utilized for on-demand drug release. Various types of materials ranging from polymers to ceramics and metals have been utilized as parts of conductive tissue engineering scaffolds, having conductivity assortments from a range of semi-conductive to conductive. The cellular and molecular activity can also be affected by the microstructure; therefore, the fabrication methods should be evaluated along with an appropriate selection of conductive materials. This review aims to address the research progress toward the use of electrically conductive materials for the modulation of cellular response at the material-tissue interface for tissue engineering applications.https://www.mdpi.com/2218-273X/9/9/448electrically conductive materialscell responsebiomaterialsnanomaterialsinterfacetissue engineeringregenerative medicine |
| spellingShingle | Azadeh Saberi Farzaneh Jabbari Payam Zarrintaj Mohammad Reza Saeb Masoud Mozafari Electrically Conductive Materials: Opportunities and Challenges in Tissue Engineering Biomolecules electrically conductive materials cell response biomaterials nanomaterials interface tissue engineering regenerative medicine |
| title | Electrically Conductive Materials: Opportunities and Challenges in Tissue Engineering |
| title_full | Electrically Conductive Materials: Opportunities and Challenges in Tissue Engineering |
| title_fullStr | Electrically Conductive Materials: Opportunities and Challenges in Tissue Engineering |
| title_full_unstemmed | Electrically Conductive Materials: Opportunities and Challenges in Tissue Engineering |
| title_short | Electrically Conductive Materials: Opportunities and Challenges in Tissue Engineering |
| title_sort | electrically conductive materials opportunities and challenges in tissue engineering |
| topic | electrically conductive materials cell response biomaterials nanomaterials interface tissue engineering regenerative medicine |
| url | https://www.mdpi.com/2218-273X/9/9/448 |
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