Induced pluripotent stem cell-derived mesenchymal stem cells activate quiescent T cells and elevate regulatory T cell response via NF-κB in allergic rhinitis patients

Induced pluripotent stem cell-derived mesenchymal stem cells activate quiescent T cells and elevate regulatory T cell response via NF-κB in allergic rhinitis patients

Abstract Background It has been demonstrated previously that induced pluripotent stem cell (iPSC)-derived mesenchymal stem cells (MSCs) have immunosuppressive effects on activated T cells. However, the effects of iPSC-MSCs on quiescent T cells are still unknown. The aim of this study was to identify...

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Bibliographic Details
Main Authors: Xing-Liang Fan, Qing-Xiang Zeng, Xin Li, Cheng-Lin Li, Zhi-Bin Xu, Xue-Quan Deng, Jianbo Shi, Dong Chen, Song Guo Zheng, Qing-Ling Fu
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Stem Cell Research & Therapy
Subjects:
Induced pluripotent stem cell-derived mesenchymal stem cells
Allergic rhinitis
Quiescent T cells
Immunomodulation
NF-κB
Online Access:http://link.springer.com/article/10.1186/s13287-018-0896-z

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