Possible link of different slow calcium signals generated by membrane potential and hormones to differential gene expression in cultured muscle cells

We studied the effect of IGF-I, insulin and testosterone on intracellular Ca2+ in cultured muscle cells. Insulin produced a fast (<1 s) and transient [Ca2+] increase lasting less than 10 s. IGF-I induced a transient [Ca2+] increase, reaching a fluorescence peak 6 s after stimulus, to return to ba...

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Bibliographic Details
Main Authors: ENRIQUE JAIMOVICH, ALEJANDRA ESPINOSA
Format: Article
Language:English
Published: BMC 2004-01-01
Series:Biological Research
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400018