Botulinum Toxin in Pediatric Neurology
Botulinum neurotoxins are natural molecules produced by anaerobic spore-forming bacteria called Clostradium boltulinum . The toxin has a peculiar mechanism of action by preventing the release of acetylcholine from the presynaptic membrane. Consequently, it has been used in the treatment of various n...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2015-06-01
|
| Series: | Global Pediatric Health |
| Online Access: | https://doi.org/10.1177/2333794X15590149 |
| _version_ | 1818403620843945984 |
|---|---|
| author | Eman M. I. Moawad MD Enas Abdallah Ali Abdallah MD |
| author_facet | Eman M. I. Moawad MD Enas Abdallah Ali Abdallah MD |
| author_sort | Eman M. I. Moawad MD |
| collection | DOAJ |
| description | Botulinum neurotoxins are natural molecules produced by anaerobic spore-forming bacteria called Clostradium boltulinum . The toxin has a peculiar mechanism of action by preventing the release of acetylcholine from the presynaptic membrane. Consequently, it has been used in the treatment of various neurological conditions related to muscle hyperactivity and/or spasticity. Also, it has an impact on the autonomic nervous system by acting on smooth muscle, leading to its use in the management of pain syndromes. The use of botulinum toxin in children separate from adults has received very little attention in the literature. This review presents the current data on the use of botulinum neurotoxin to treat various neurological disorders in children. |
| first_indexed | 2024-12-14T08:27:10Z |
| format | Article |
| id | doaj.art-ac1207e789214ca2bda27fc62dd1a610 |
| institution | Directory Open Access Journal |
| issn | 2333-794X |
| language | English |
| last_indexed | 2024-12-14T08:27:10Z |
| publishDate | 2015-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Global Pediatric Health |
| spelling | doaj.art-ac1207e789214ca2bda27fc62dd1a6102022-12-21T23:09:36ZengSAGE PublishingGlobal Pediatric Health2333-794X2015-06-01210.1177/2333794X1559014910.1177_2333794X15590149Botulinum Toxin in Pediatric NeurologyEman M. I. Moawad MD0Enas Abdallah Ali Abdallah MD1Cairo University, Cairo, EgyptCairo University, Cairo, EgyptBotulinum neurotoxins are natural molecules produced by anaerobic spore-forming bacteria called Clostradium boltulinum . The toxin has a peculiar mechanism of action by preventing the release of acetylcholine from the presynaptic membrane. Consequently, it has been used in the treatment of various neurological conditions related to muscle hyperactivity and/or spasticity. Also, it has an impact on the autonomic nervous system by acting on smooth muscle, leading to its use in the management of pain syndromes. The use of botulinum toxin in children separate from adults has received very little attention in the literature. This review presents the current data on the use of botulinum neurotoxin to treat various neurological disorders in children.https://doi.org/10.1177/2333794X15590149 |
| spellingShingle | Eman M. I. Moawad MD Enas Abdallah Ali Abdallah MD Botulinum Toxin in Pediatric Neurology Global Pediatric Health |
| title | Botulinum Toxin in Pediatric Neurology |
| title_full | Botulinum Toxin in Pediatric Neurology |
| title_fullStr | Botulinum Toxin in Pediatric Neurology |
| title_full_unstemmed | Botulinum Toxin in Pediatric Neurology |
| title_short | Botulinum Toxin in Pediatric Neurology |
| title_sort | botulinum toxin in pediatric neurology |
| url | https://doi.org/10.1177/2333794X15590149 |
| work_keys_str_mv | AT emanmimoawadmd botulinumtoxininpediatricneurology AT enasabdallahaliabdallahmd botulinumtoxininpediatricneurology |