Atorvastatin Improves Microenvironment to Enhance the Beneficial Effects of BMSCs Therapy in a Rabbit Model of Acute Myocardial Infarction

Atorvastatin Improves Microenvironment to Enhance the Beneficial Effects of BMSCs Therapy in a Rabbit Model of Acute Myocardial Infarction

Background/Aims: To investigate the beneficial effects of atorvastatin added to the cell therapy with bone marrow-derived mesenchymal stromal cells (BMSCs) in a rabbit model of acute myocardial infarction (AMI). Methods: Rabbits were randomly divided into control group (n=10), bone marrow stem cells...

Full description

Bibliographic Details
Main Authors:	Zhe Qu, Hongxin Xu, Yihao Tian, Xuejun Jiang
Format:	Article
Language:	English
Published:	Cell Physiol Biochem Press GmbH & Co KG 2013-08-01
Series:	Cellular Physiology and Biochemistry
Subjects:	Cell survival Atorvastatin Bone marrow stem cells (BMSCs) Transplantation Acute myocardial infarction Cardiac function Apoptosis
Online Access:	http://www.karger.com/Article/FullText/354445

Similar Items

Effects of single-dose atorvastatin on interleukin-6, interferon gamma, and myocardial no-reflow in a rabbit model of acute myocardial infarction and reperfusion
by: X.J. Zhao, et al.
Published: (2014-03-01)

Dose-dependent effects of atorvastatin in the hospitalisation period of myocardial infarction
by: O. L. Barbarash, et al.
Published: (2013-06-01)

Effect of Very Early Atorvastatin Initiation for Acute Myocardial Infarction on Creatine Kinase release
by: Faris Abdul Kareem, et al.
Published: (2010-06-01)

Protective effects of atorvastatin and quercetin on isoprenaline-induced myocardial infarction in rats
by: Mai A. Zaafan, et al.
Published: (2013-06-01)

ASPECTS OF LIPID-LOWERING THERAPY WITH ATORVASTATIN IN PATIENTS WITH MYOCARDIAL INFARCTION FROM THE PERSPECTIVE OF PERSONALIZED MEDICINE
by: M. V. Solodun, et al.
Published: (2015-09-01)

SDF-1α upregulation by atorvastatin in rats with acute myocardial infarction via nitric oxide production confers anti-inflammatory and anti-apoptotic effects
by: Qiu Ruofeng, et al.
Published: (2012-11-01)

Early effects of atorvastatin on Vitamin D and parathyroid hormone serum levels following acute myocardial infarction
by: Batool Zarei, et al.
Published: (2019-01-01)

Atorvastatin-pretreated mesenchymal stem cell-derived extracellular vesicles promote cardiac repair after myocardial infarction via shifting macrophage polarization by targeting microRNA-139-3p/Stat1 pathway
by: Yu Ning, et al.
Published: (2023-03-01)

Comparative effects of atorvastatin 80 mg and rosuvastatin 40 mg on the levels of serum endocan, chemerin, and galectin-3 in patients with acute myocardial infarction
by: Abdullah Tunçez, et al.
Published: (2019-11-01)

RNA Sequencing Reveals Beneficial Effects of Atorvastatin on Endothelial Cells in Acute Kawasaki Disease
by: Chisato Shimizu, et al.
Published: (2022-07-01)

Evaluation of high dose atorvastatin therapy 24 hours before elective percutaneous coronary intervention on peri-PCI myocardial infarction
by: Rahmani R, et al.
Published: (2013-02-01)

Silencing HIF-1α reduces the adhesion and secretion functions of acute leukemia hBMSCs
by: Zeng Dong-Feng, et al.
Published: (2012-10-01)

DEX‐Induced SREBF1 Promotes BMSCs Differentiation into Adipocytes to Attract and Protect Residual T‐Cell Acute Lymphoblastic Leukemia Cells After Chemotherapy
by: Ruinan Jia, et al.
Published: (2023-07-01)

Crosstalk between CML cells with HUVECs and BMSCs through exosomes
by: Zafer Cetin, et al.
Published: (2020-10-01)

ASPH Regulates Osteogenic Differentiation and Cellular Senescence of BMSCs
by: Hui Peng, et al.
Published: (2020-09-01)

Effect of atorvastatin nanoparticles compared to free atrovastatin on plaque properties in rabbit model of atherosclerosis
by: Anjuman Arora, et al.
Published: (2019-01-01)

A silk fibroin/chitosan/nanohydroxyapatite biomimetic bone scaffold combined with autologous concentrated growth factor promotes the proliferation and osteogenic differentiation of BMSCs and repair of critical bone defects
by: Yi Zhou, et al.
Published: (2022-12-01)

Combined Beneficial Effect of Genistein and Atorvastatin on Adipogenesis in 3T3-L1 Adipocytes
by: Dahae Lee, et al.
Published: (2021-07-01)

Atorvastatin alleviates cardiomyocyte apoptosis by suppressing TRB3 induced by acute myocardial infarction and hypoxia
by: Wen-Pin Cheng, et al.
Published: (2017-05-01)

STATINS AND PERCUTANEOUS CORONARY INTERVENTION. FOCUS ON THE ATORVASTATIN
by: N. G. Gogolashvili
Published: (2015-09-01)

Neurotrophin-3 Promotes the Neuronal Differentiation of BMSCs and Improves Cognitive Function in a Rat Model of Alzheimer's Disease
by: Zhongrui Yan, et al.
Published: (2021-02-01)

Transplantation of Bone Marrow Derived Progenitor Cells in Acute Myocardial Infarction. The First Results
by: Radek Pudil, et al.
Published: (2005-01-01)

Glutamate regulates gliosis of BMSCs to promote ENS regeneration through α-KG and H3K9/H3K27 demethylation
by: Mengke Fan, et al.
Published: (2022-06-01)

Comparison of the incidence of contrast-induced nephropathy after primary PCI in patients receiving high-dose rosuvastatin and atorvastatin
by: Samad Golshani, et al.
Published: (2022-01-01)

Simultaneous administration of high-dose atorvastatin and clopidogrel does not interfere with platelet inhibition during percutaneous coronary intervention
by: Kreutz RP, et al.
Published: (2016-06-01)

LONG TERM CLINICAL RESULTS OF AUTOLOGOUS CD133+ BONE MARROW CELLS TRANSPLANTATION IN ST ELEVATION MYOCARDIAL INFARCTION PATIENTS
by: M. A. Kirgizova, et al.
Published: (2016-03-01)

Acylation-stimulating protein is a surrogate biomarker for acute myocardial infarction: Role of statins
by: Hayder M. Al-Kuraishy, et al.
Published: (2017-07-01)

Comparison of the Treatment Efficacy of Rosuvastatin versus Atorvastatin Loading Prior to Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction
by: Esraa M. Adel, et al.
Published: (2022-08-01)

Mesh-like electrospun membrane loaded with atorvastatin facilitates cutaneous wound healing by promoting the paracrine function of mesenchymal stem cells
by: Jieyu Xiang, et al.
Published: (2022-05-01)

Chitosan– Gelatin (Ch-G) Thin Membrane with Bone Marrow Mesenchymal Stem Cells (BMSCs): A New Model As A Dressing Bandage
by: A. Emamgholi, et al.
Published: (2015-05-01)

IL-8 Enhances Therapeutic Effects of BMSCs on Bone Regeneration via CXCR2-Mediated PI3k/Akt Signaling Pathway
by: Aijun Yang, et al.
Published: (2018-07-01)

In vitro determination of osteo-adipogenic lineage choice of bone marrow stromal/stem cells (BMSCs)
by: Dawei Qiu, et al.
Published: (2024-06-01)

Vasoprotective effect of effective lipid-lowering therapy in patients with <i>ST</i>-segment elevation myocardial infarction
by: Ludmila I. Salyamova, et al.
Published: (2023-01-01)

Atorvastatin suppresses lipopolysaccharide-induced inflammation in human coronary artery endothelial cells
by: Zhen Tian, et al.
Published: (2022-04-01)

TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs
by: Xiaonan Liang, et al.
Published: (2021-08-01)

A comparative study on the effects of niacin plus atorvastatin with that of fenofibrate plus atorvastatin in dyslipidemia
by: Selim Ahmed, et al.
Published: (2008-04-01)

A comparative study on the effects of niacin plus atorvastatin with that of fenofibrate plus atorvastatin in dyslipidemia
by: Salim Ahmed, et al.
Published: (2008-06-01)

Can atorvastatin calcium cause asymptomatic hypercalcemia?
by: Suleyman Hilmi Ipekci, et al.
Published: (2014-10-01)

Evaluation of periodontal health in patients taking atorvastatin
by: Kosar Rezaei Talarposhti, et al.
Published: (2018-09-01)

Treatment of heart failure after myocardial infarction with bone marrow-derived mesenchymal stem cells
by: Hong Yu, et al.
Published: (2016-01-01)