Slow-growing amelanotic malignant melanoma of the esophagus with long survival: a case report and review of the literature

Background and study aims We report a case of amelanotic malignant melanoma of the esophagus (AMME), an exceedingly rare disease. A 77-year-old Japanese woman presented to our hospital with features suggestive of a middle esophageal submucosal tumor, which was diagnosed pathologically as AMME. The p...

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Main Authors: Yutaka Hirayama, Tajika Masahiro, Tsutomu Tanaka, Makoto Ishihara, Sachiyo Ohnishi, Kazuo Hara, Nobumasa Mizuno, Susumu Hijioka, Nozomi Okuno, Tetsuya Abe, Norihisa Uemura, Jiro Kawakami, Shintarou Kurahashi, Yasuhiro Shimizu, Yasushi Yatabe, Yasumasa Niwa
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2017-10-01
Series:Endoscopy International Open
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-117951
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author Yutaka Hirayama
Tajika Masahiro
Tsutomu Tanaka
Makoto Ishihara
Sachiyo Ohnishi
Kazuo Hara
Nobumasa Mizuno
Susumu Hijioka
Nozomi Okuno
Tetsuya Abe
Norihisa Uemura
Jiro Kawakami
Shintarou Kurahashi
Yasuhiro Shimizu
Yasushi Yatabe
Yasumasa Niwa
author_facet Yutaka Hirayama
Tajika Masahiro
Tsutomu Tanaka
Makoto Ishihara
Sachiyo Ohnishi
Kazuo Hara
Nobumasa Mizuno
Susumu Hijioka
Nozomi Okuno
Tetsuya Abe
Norihisa Uemura
Jiro Kawakami
Shintarou Kurahashi
Yasuhiro Shimizu
Yasushi Yatabe
Yasumasa Niwa
author_sort Yutaka Hirayama
collection DOAJ
description Background and study aims We report a case of amelanotic malignant melanoma of the esophagus (AMME), an exceedingly rare disease. A 77-year-old Japanese woman presented to our hospital with features suggestive of a middle esophageal submucosal tumor, which was diagnosed pathologically as AMME. The patient underwent thoracoscopic resection of the esophagus and laparoscopic gastric tube reconstruction. Three years after surgery, computed tomography showed no recurrence. Generally, the prognosis of malignant melanoma of the esophagus is very poor. However, our patient had no recurrence, and is alive 3 years after surgery and 5 years after the tumor was first detected.
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spelling doaj.art-ac1599efb0524a019b1819eae9d033662022-12-22T00:59:43ZengGeorg Thieme Verlag KGEndoscopy International Open2364-37222196-97362017-10-010511E1076E108010.1055/s-0043-117951Slow-growing amelanotic malignant melanoma of the esophagus with long survival: a case report and review of the literatureYutaka Hirayama0Tajika Masahiro1Tsutomu Tanaka2Makoto Ishihara3Sachiyo Ohnishi4Kazuo Hara5Nobumasa Mizuno6Susumu Hijioka7Nozomi Okuno8Tetsuya Abe9Norihisa Uemura10Jiro Kawakami11Shintarou Kurahashi12Yasuhiro Shimizu13Yasushi Yatabe14Yasumasa Niwa15Department of Endoscopy, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Endoscopy, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Endoscopy, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Endoscopy, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Endoscopy, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Gastroenterology, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Gastroenterology, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Gastroenterology, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Gastroenterology, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Gastroenterological Surgery, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Gastroenterological Surgery, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Gastroenterological Surgery, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Gastroenterological Surgery, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Gastroenterological Surgery, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Pathology and Molecular Diagnosis, Aichi Cancer Center Hospital, Aichi, JapanDepartment of Endoscopy, Aichi Cancer Center Hospital, Aichi, JapanBackground and study aims We report a case of amelanotic malignant melanoma of the esophagus (AMME), an exceedingly rare disease. A 77-year-old Japanese woman presented to our hospital with features suggestive of a middle esophageal submucosal tumor, which was diagnosed pathologically as AMME. The patient underwent thoracoscopic resection of the esophagus and laparoscopic gastric tube reconstruction. Three years after surgery, computed tomography showed no recurrence. Generally, the prognosis of malignant melanoma of the esophagus is very poor. However, our patient had no recurrence, and is alive 3 years after surgery and 5 years after the tumor was first detected.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-117951
spellingShingle Yutaka Hirayama
Tajika Masahiro
Tsutomu Tanaka
Makoto Ishihara
Sachiyo Ohnishi
Kazuo Hara
Nobumasa Mizuno
Susumu Hijioka
Nozomi Okuno
Tetsuya Abe
Norihisa Uemura
Jiro Kawakami
Shintarou Kurahashi
Yasuhiro Shimizu
Yasushi Yatabe
Yasumasa Niwa
Slow-growing amelanotic malignant melanoma of the esophagus with long survival: a case report and review of the literature
Endoscopy International Open
title Slow-growing amelanotic malignant melanoma of the esophagus with long survival: a case report and review of the literature
title_full Slow-growing amelanotic malignant melanoma of the esophagus with long survival: a case report and review of the literature
title_fullStr Slow-growing amelanotic malignant melanoma of the esophagus with long survival: a case report and review of the literature
title_full_unstemmed Slow-growing amelanotic malignant melanoma of the esophagus with long survival: a case report and review of the literature
title_short Slow-growing amelanotic malignant melanoma of the esophagus with long survival: a case report and review of the literature
title_sort slow growing amelanotic malignant melanoma of the esophagus with long survival a case report and review of the literature
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-117951
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