High extracellular phosphate increases platelet polyphosphate content

Platelet-derived extracellular polyphosphate (PolyP) is a major mediator of thrombosis. PolyP is a linear chain of inorganic phosphate (Pi) and is stored in platelet dense granules. Pi enters cells from the extracellular fluid through phosphate transporters and may be stored as PolyP. Here we show t...

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Bibliographic Details
Main Authors: Nima Abbasian, Matthew T. Harper
Format: Article
Language:English
Published: Taylor & Francis Group 2021-10-01
Series:Platelets
Subjects:
Online Access:http://dx.doi.org/10.1080/09537104.2020.1817358