Therapeutic Potential and Molecular Mechanisms of Emblica officinalis Gaertn in countering nephrotoxicity in rats induced by the chemotherapeutic agent cisplatin

Therapeutic Potential and Molecular Mechanisms of Emblica officinalis Gaertn in countering nephrotoxicity in rats induced by the chemotherapeutic agent cisplatin

Emblica officinalis Gaertn. belonging to family Euphorbiaceae is commonly known as Indian gooseberry or Amla in India. It is used as a ‘rejuvenating herb’ in traditional system of Indian medicine. It has been shown to possess antioxidant, anti-inflammatory and anti-apoptotic effects. Thus, on the ba...

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Main Authors: Salma Malik, Kapil Suchal, Jagriti Bhatia, Sana Irfan Khan, Swati Vashishtha, Ameesha Tomar, Sameer Goyal, Rajeev Kumar, Dharamvir Singh Arya, Shreesh K Ojha
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Pharmacology
Subjects:
Apoptosis
Cisplatin
Inflammation
Oxidative Stress
nephrotoxicity
Emblica officinalis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00350/full

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