Visceral adipose index, lipid accumulation product, and selected cardiometabolic risk markers among postmenopausal Sudanese women: A cross-sectional study

Background: In Sub-Saharan African countries, data examining postmenopausal women's cardiometabolic risk (CMR) remains limited. Our study aimed to assess the visceral adiposity index (VAI) and lipid accumulation product (LAP), atherogenic index of plasma (AIP), and physical activity levels of p...

Full description

Bibliographic Details
Main Authors: Ahlam Badreldin El Shikieri, Abdelgadir Elmugadam, Ghada A. Elfadil
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Human Nutrition & Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666149723000397
_version_ 1797435742982504448
author Ahlam Badreldin El Shikieri
Abdelgadir Elmugadam
Ghada A. Elfadil
author_facet Ahlam Badreldin El Shikieri
Abdelgadir Elmugadam
Ghada A. Elfadil
author_sort Ahlam Badreldin El Shikieri
collection DOAJ
description Background: In Sub-Saharan African countries, data examining postmenopausal women's cardiometabolic risk (CMR) remains limited. Our study aimed to assess the visceral adiposity index (VAI) and lipid accumulation product (LAP), atherogenic index of plasma (AIP), and physical activity levels of postmenopausal women and determine their CMR. Methods: A cross-sectional study included 224 postmenopausal women aged ≥47 years recruited from Khartoum State, Sudan. Weight, height, waist and hip circumferences were measured. Physical activity levels were determined using the Global Physical Activity Questionnaire version 2. Fasting blood samples (5 mL) were collected to determine the lipid profile. The VAI and LAP were calculated as indicators for visceral adiposity, whereas AIP was calculated as an indicator of CVD risk. Results: The postmenopausal women's mean age was 62.4 ± 10.2 years. Women (29.2%; 54/185) were physically inactive, with most inactive women being >64 years and having ≥5 CVD risk factors compared with the active and very active women with 3–4 CVD risk factors. Women had high total cholesterol (24.6%), triglycerides (26.6%), low-density lipoprotein cholesterol (14.3%), and low high-density lipoprotein cholesterol (61.2%) levels. Moreover, women (33.5%) had a high CVD risk. In multiple regression analyses, AIP increased significantly with VAI and BMI. The ROC analysis revealed that the highest and statistically significant AUC was recorded for VAI followed by LAP among postmenopausal women, suggesting their diagnostic significance for CVD risk. Conclusion: VAI and LAP were closely associated with an increased risk of CVD in postmenopausal Sudanese women and were considered the best diagnostic performance.
first_indexed 2024-03-09T10:52:39Z
format Article
id doaj.art-ac22f7dc847d4c8bb647bf71a74a970c
institution Directory Open Access Journal
issn 2666-1497
language English
last_indexed 2024-03-09T10:52:39Z
publishDate 2023-12-01
publisher Elsevier
record_format Article
series Human Nutrition & Metabolism
spelling doaj.art-ac22f7dc847d4c8bb647bf71a74a970c2023-12-01T05:03:05ZengElsevierHuman Nutrition & Metabolism2666-14972023-12-0134200222Visceral adipose index, lipid accumulation product, and selected cardiometabolic risk markers among postmenopausal Sudanese women: A cross-sectional studyAhlam Badreldin El Shikieri0Abdelgadir Elmugadam1Ghada A. Elfadil2College of Applied Medical Sciences, Department of Clinical Nutrition, Taibah University, Al Madinah Al Munawarah, Saudi ArabiaDepartment of Clinical Chemistry, College of Medical Laboratory Science, Sudan University of Science and Technology, Khartoum, SudanDepartment of Clinical Chemistry, College of Medical Laboratory Science, Sudan University of Science and Technology, Khartoum, Sudan; Corresponding author.Background: In Sub-Saharan African countries, data examining postmenopausal women's cardiometabolic risk (CMR) remains limited. Our study aimed to assess the visceral adiposity index (VAI) and lipid accumulation product (LAP), atherogenic index of plasma (AIP), and physical activity levels of postmenopausal women and determine their CMR. Methods: A cross-sectional study included 224 postmenopausal women aged ≥47 years recruited from Khartoum State, Sudan. Weight, height, waist and hip circumferences were measured. Physical activity levels were determined using the Global Physical Activity Questionnaire version 2. Fasting blood samples (5 mL) were collected to determine the lipid profile. The VAI and LAP were calculated as indicators for visceral adiposity, whereas AIP was calculated as an indicator of CVD risk. Results: The postmenopausal women's mean age was 62.4 ± 10.2 years. Women (29.2%; 54/185) were physically inactive, with most inactive women being >64 years and having ≥5 CVD risk factors compared with the active and very active women with 3–4 CVD risk factors. Women had high total cholesterol (24.6%), triglycerides (26.6%), low-density lipoprotein cholesterol (14.3%), and low high-density lipoprotein cholesterol (61.2%) levels. Moreover, women (33.5%) had a high CVD risk. In multiple regression analyses, AIP increased significantly with VAI and BMI. The ROC analysis revealed that the highest and statistically significant AUC was recorded for VAI followed by LAP among postmenopausal women, suggesting their diagnostic significance for CVD risk. Conclusion: VAI and LAP were closely associated with an increased risk of CVD in postmenopausal Sudanese women and were considered the best diagnostic performance.http://www.sciencedirect.com/science/article/pii/S2666149723000397Postmenopausal womenVisceral adiposity indexPhysical activityCardiovascular diseaseSudan
spellingShingle Ahlam Badreldin El Shikieri
Abdelgadir Elmugadam
Ghada A. Elfadil
Visceral adipose index, lipid accumulation product, and selected cardiometabolic risk markers among postmenopausal Sudanese women: A cross-sectional study
Human Nutrition & Metabolism
Postmenopausal women
Visceral adiposity index
Physical activity
Cardiovascular disease
Sudan
title Visceral adipose index, lipid accumulation product, and selected cardiometabolic risk markers among postmenopausal Sudanese women: A cross-sectional study
title_full Visceral adipose index, lipid accumulation product, and selected cardiometabolic risk markers among postmenopausal Sudanese women: A cross-sectional study
title_fullStr Visceral adipose index, lipid accumulation product, and selected cardiometabolic risk markers among postmenopausal Sudanese women: A cross-sectional study
title_full_unstemmed Visceral adipose index, lipid accumulation product, and selected cardiometabolic risk markers among postmenopausal Sudanese women: A cross-sectional study
title_short Visceral adipose index, lipid accumulation product, and selected cardiometabolic risk markers among postmenopausal Sudanese women: A cross-sectional study
title_sort visceral adipose index lipid accumulation product and selected cardiometabolic risk markers among postmenopausal sudanese women a cross sectional study
topic Postmenopausal women
Visceral adiposity index
Physical activity
Cardiovascular disease
Sudan
url http://www.sciencedirect.com/science/article/pii/S2666149723000397
work_keys_str_mv AT ahlambadreldinelshikieri visceraladiposeindexlipidaccumulationproductandselectedcardiometabolicriskmarkersamongpostmenopausalsudanesewomenacrosssectionalstudy
AT abdelgadirelmugadam visceraladiposeindexlipidaccumulationproductandselectedcardiometabolicriskmarkersamongpostmenopausalsudanesewomenacrosssectionalstudy
AT ghadaaelfadil visceraladiposeindexlipidaccumulationproductandselectedcardiometabolicriskmarkersamongpostmenopausalsudanesewomenacrosssectionalstudy