Sphere-induced reprogramming of RPE cells into dual-potential RPE stem-like cells

Sphere-induced reprogramming of RPE cells into dual-potential RPE stem-like cells

Background: The retinal pigment epithelium (RPE) has the potential to regenerate the entire neuroretina upon retinal injury in amphibians. In contrast, this regenerative capacity has been lost in mammals. The reprogramming of differentiated somatic cells into induced pluripotent stem cells (iPSCs) b...

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Bibliographic Details
Main Authors: Fenghua Chen, Xiao Liu, Yao Chen, John Y. Liu, Huayi Lu, Wei Wang, Xiaoqin Lu, Kevin C. Dean, Ling Gao, Henry J. Kaplan, Douglas C. Dean, Xiaoyan Peng, Yongqing Liu
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419308333

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