Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis

Oogenesis depends on close interaction between germ cells and the surrounding somatic niche. Here the authors demonstrate that Eya controls bilateral affinity at the germline-soma interface to generate self-organizing inter-lineage units that ensure oocyte maturation.

Bibliographic Details
Main Authors: Vanessa Weichselberger, Patrick Dondl, Anne-Kathrin Classen
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33845-1
_version_ 1811335136223952896
author Vanessa Weichselberger
Patrick Dondl
Anne-Kathrin Classen
author_facet Vanessa Weichselberger
Patrick Dondl
Anne-Kathrin Classen
author_sort Vanessa Weichselberger
collection DOAJ
description Oogenesis depends on close interaction between germ cells and the surrounding somatic niche. Here the authors demonstrate that Eya controls bilateral affinity at the germline-soma interface to generate self-organizing inter-lineage units that ensure oocyte maturation.
first_indexed 2024-04-13T17:19:39Z
format Article
id doaj.art-ac253080c3fd415c83791172a5df6a4d
institution Directory Open Access Journal
issn 2041-1723
language English
last_indexed 2024-04-13T17:19:39Z
publishDate 2022-10-01
publisher Nature Portfolio
record_format Article
series Nature Communications
spelling doaj.art-ac253080c3fd415c83791172a5df6a4d2022-12-22T02:38:02ZengNature PortfolioNature Communications2041-17232022-10-0113111710.1038/s41467-022-33845-1Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesisVanessa Weichselberger0Patrick Dondl1Anne-Kathrin Classen2Hilde-Mangold-Haus, University of FreiburgDepartment for Applied Mathematics, University of FreiburgHilde-Mangold-Haus, University of FreiburgOogenesis depends on close interaction between germ cells and the surrounding somatic niche. Here the authors demonstrate that Eya controls bilateral affinity at the germline-soma interface to generate self-organizing inter-lineage units that ensure oocyte maturation.https://doi.org/10.1038/s41467-022-33845-1
spellingShingle Vanessa Weichselberger
Patrick Dondl
Anne-Kathrin Classen
Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis
Nature Communications
title Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis
title_full Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis
title_fullStr Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis
title_full_unstemmed Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis
title_short Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis
title_sort eya controlled affinity between cell lineages drives tissue self organization during drosophila oogenesis
url https://doi.org/10.1038/s41467-022-33845-1
work_keys_str_mv AT vanessaweichselberger eyacontrolledaffinitybetweencelllineagesdrivestissueselforganizationduringdrosophilaoogenesis
AT patrickdondl eyacontrolledaffinitybetweencelllineagesdrivestissueselforganizationduringdrosophilaoogenesis
AT annekathrinclassen eyacontrolledaffinitybetweencelllineagesdrivestissueselforganizationduringdrosophilaoogenesis