Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis
Oogenesis depends on close interaction between germ cells and the surrounding somatic niche. Here the authors demonstrate that Eya controls bilateral affinity at the germline-soma interface to generate self-organizing inter-lineage units that ensure oocyte maturation.
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-33845-1 |
_version_ | 1811335136223952896 |
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author | Vanessa Weichselberger Patrick Dondl Anne-Kathrin Classen |
author_facet | Vanessa Weichselberger Patrick Dondl Anne-Kathrin Classen |
author_sort | Vanessa Weichselberger |
collection | DOAJ |
description | Oogenesis depends on close interaction between germ cells and the surrounding somatic niche. Here the authors demonstrate that Eya controls bilateral affinity at the germline-soma interface to generate self-organizing inter-lineage units that ensure oocyte maturation. |
first_indexed | 2024-04-13T17:19:39Z |
format | Article |
id | doaj.art-ac253080c3fd415c83791172a5df6a4d |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-04-13T17:19:39Z |
publishDate | 2022-10-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-ac253080c3fd415c83791172a5df6a4d2022-12-22T02:38:02ZengNature PortfolioNature Communications2041-17232022-10-0113111710.1038/s41467-022-33845-1Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesisVanessa Weichselberger0Patrick Dondl1Anne-Kathrin Classen2Hilde-Mangold-Haus, University of FreiburgDepartment for Applied Mathematics, University of FreiburgHilde-Mangold-Haus, University of FreiburgOogenesis depends on close interaction between germ cells and the surrounding somatic niche. Here the authors demonstrate that Eya controls bilateral affinity at the germline-soma interface to generate self-organizing inter-lineage units that ensure oocyte maturation.https://doi.org/10.1038/s41467-022-33845-1 |
spellingShingle | Vanessa Weichselberger Patrick Dondl Anne-Kathrin Classen Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis Nature Communications |
title | Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis |
title_full | Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis |
title_fullStr | Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis |
title_full_unstemmed | Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis |
title_short | Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis |
title_sort | eya controlled affinity between cell lineages drives tissue self organization during drosophila oogenesis |
url | https://doi.org/10.1038/s41467-022-33845-1 |
work_keys_str_mv | AT vanessaweichselberger eyacontrolledaffinitybetweencelllineagesdrivestissueselforganizationduringdrosophilaoogenesis AT patrickdondl eyacontrolledaffinitybetweencelllineagesdrivestissueselforganizationduringdrosophilaoogenesis AT annekathrinclassen eyacontrolledaffinitybetweencelllineagesdrivestissueselforganizationduringdrosophilaoogenesis |