ANGPT2/CAV1 regulates albumin transcytosis of glomerular endothelial cells under high glucose exposure and is impaired by losartan

ANGPT2/CAV1 regulates albumin transcytosis of glomerular endothelial cells under high glucose exposure and is impaired by losartan

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Background: Microalbuminuria is a common clinical symptom that manifests in the early stages of diabetic kidney disease (DKD) and is also the main feature of glomerular endothelial cells (GECs) injury. There is increasing evidence that the transcytosis of albumin across GECs is closely related to th...

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Bibliographic Details
Main Authors: Yang Chen, Huiqing Li, Di Zhang, Yi Gong, Huajun Jiang, Hui Sun, Yumei Wang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Nefrología (English Edition)
Subjects:
Enfermedad renal diabética
Célula endotelial glomerular
Transcitosis de la albúmina
Angiopoyetina 2
Caveolina 1
Losartan
Online Access:http://www.sciencedirect.com/science/article/pii/S2013251423000317

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http://www.sciencedirect.com/science/article/pii/S2013251423000317

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