A Functional Polymorphism-Mediated Disruption of EGR1/ADAM10 Pathway Confers the Risk of Sepsis Progression

A Functional Polymorphism-Mediated Disruption of EGR1/ADAM10 Pathway Confers the Risk of Sepsis Progression

ABSTRACT Increasing evidence has indicated that single nucleotide polymorphisms (SNPs) are related to the susceptibility of sepsis and might provide potential evidence for the mechanisms of sepsis. Our recent preliminary study showed that the ADAM10 genetic polymorphism was clinically associated wit...

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Bibliographic Details
Main Authors: Feng Chen, Yan Wang, Wenying Zhang, Yujie Cai, Tian Zhao, Hui Mai, Shoubao Tao, Wenyan Wei, Jia Li, Xiongjin Chen, Xiaohui Li, Pei Tang, Weihao Fan, Jingqi Yang, Mingqian Ou, Furong Lu, Zhipeng Lai, Huiyi Chen, Ting Zou, Furong Sun, Yiming Shao, Lili Cui
Format: Article
Language:English
Published: American Society for Microbiology 2019-08-01
Series:mBio
Subjects:
ADAM10
EGR1
polymorphism
rs653765
sepsis
Online Access:https://journals.asm.org/doi/10.1128/mBio.01663-19

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