Solubility Determination of c-Met Inhibitor in Solvent Mixtures and Mathematical Modeling to Develop Nanosuspension Formulation
The solubility and dissolution thermodynamics of new c-Met inhibitor, ABN401, were determined in eleven solvents and Transcutol<sup>®</sup> HP–water mixture (TWM) from 298.15 to 318.15 K. The experimental solubilities were validated using five mathematical models, namely modified Apelbla...
Main Authors: | Maharjan Ravi, Tripathi Julu, Nam Ah Kim, Kyeung Eui Park, Seong Hoon Jeong |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-01-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/2/390 |
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