Clinical characteristics and outcomes of critically ill mechanically ventilated COVID-19 patients receiving interleukin-6 receptor antagonists and corticosteroid therapy: a preliminary report from a multinational registry

Clinical characteristics and outcomes of critically ill mechanically ventilated COVID-19 patients receiving interleukin-6 receptor antagonists and corticosteroid therapy: a preliminary report from a multinational registry

Abstract Background Interleukin-6 receptor antagonists (IL-6RAs) and steroids are emerging immunomodulatory therapies for severe and critical coronavirus disease (COVID-19). In this preliminary report, we aim to describe the epidemiology, clinical characteristics, and outcomes of adult critically il...

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Main Authors: Marwa Amer, Ahmed M. Kamel, Mohammed Bawazeer, Khalid Maghrabi, Abid Butt, Talal Dahhan, Eiad Kseibi, Syed Moazzum Khurshid, Mohammed Abujazar, Razan Alghunaim, Muath Rabee, Maal Abualkhair, Ali Al-Janoubi, Abeer Turki AlFirm, Ognjen Gajic, Allan J. Walkey, Jarrod M. Mosier, Igor Borisovich Zabolotskikh, Oscar Y. Gavidia, Santiago Yus- Teruel, Michael A. Bernstein, Karen Boman, Vishakha K. Kumar, Vikas Bansal, Rahul Kashyap, the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group
Format: Article
Language:English
Published: BMC 2021-10-01
Series:European Journal of Medical Research
Subjects:
Interleukin-6
Interleukin-6 receptor antagonist
Steroid
Critical care
Coronavirus disease 2019
Invasive mechanical ventilation
Online Access:https://doi.org/10.1186/s40001-021-00591-x

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