Genome-centric analyses of 165 metagenomes show that mobile genetic elements are crucial for the transmission of antimicrobial resistance genes to pathogens in activated sludge and wastewater

Genome-centric analyses of 165 metagenomes show that mobile genetic elements are crucial for the transmission of antimicrobial resistance genes to pathogens in activated sludge and wastewater

ABSTRACTWastewater is considered a reservoir of antimicrobial resistance genes (ARGs), where the abundant antimicrobial-resistant bacteria and mobile genetic elements facilitate horizontal gene transfer. However, the prevalence and extent of these phenomena in different taxonomic groups that inhabit...

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Bibliographic Details
Main Authors: Nafi’u Abdulkadir, Joao Pedro Saraiva, Junya Zhang, Stefan Stolte, Osnat Gillor, Hauke Harms, Ulisses Rocha
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:Microbiology Spectrum
Subjects:
antimicrobial resistance genes
metagenome-assembled genomes
mobile genetic elements
wastewater
activated sludge
pathogens
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02918-23

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