Diagnosis of Chemotherapy-Induced Cardiotoxicity

Cardiotoxicity is a rising issue connected to use of chemotherapy and radiotherapy in the treatment of neoplastic diseases. Early diagnosis during follow-up is of paramount importance, and careful surveillance is recommended. Evaluation of left ventricular ejection fraction by echocardiography and n...

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Bibliographic Details
Main Authors: Fausto Pizzino, Giampiero Vizzari, Charles A. Bomzer, Rubina Qamar, Scipione Carerj, Concetta Zito, Bijoy K. Khandheria
Format: Article
Language:English
Published: Advocate Aurora Health 2014-08-01
Series:Journal of Patient-Centered Research and Reviews
Subjects:
Online Access:http://digitalrepository.aurorahealthcare.org/cgi/viewcontent.cgi?article=1025&context=jpcrr
Description
Summary:Cardiotoxicity is a rising issue connected to use of chemotherapy and radiotherapy in the treatment of neoplastic diseases. Early diagnosis during follow-up is of paramount importance, and careful surveillance is recommended. Evaluation of left ventricular ejection fraction by echocardiography and nuclear medicine techniques is widely used in clinical practice; however, their sensitivity in detecting early cardiac damage is low. New instruments like speckle-tracking imaging, cardiac magnetic resonance and cardiac circulating biomarkers are available to clinicians to best evaluate the onset and progression of cardiotoxic effects, improving the therapeutic management and final outcome for the patient.
ISSN:2330-0698