Signaling Peptide SpoV Is Essential for <i>Streptococcus pyogenes</i> Virulence, and Prophylaxis with Anti-SpoV Decreases Disease Severity

Signaling Peptide SpoV Is Essential for <i>Streptococcus pyogenes</i> Virulence, and Prophylaxis with Anti-SpoV Decreases Disease Severity

Streptococcal peptide of virulence (SpoV) is a <i>Streptococcus pyogenes</i> (group A streptococcus (GAS))-specific peptide that is important for GAS survival in murine blood, and the expression of the virulence factors streptolysin O (<i>slo</i>) and streptolysin S (<i>...

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Bibliographic Details
Main Authors: Andrea L. Herrera, Michael S. Chaussee
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Microorganisms
Subjects:
<i>Streptococcus pyogenes</i>
SpoV
virulence
iGAS
antibody therapy
Online Access:https://www.mdpi.com/2076-2607/9/11/2321

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