Medical costs and quality-adjusted life years associated with smoking: a systematic review

Abstract Background Estimated medical costs (“T”) and QALYs (“Q”) associated with smoking are frequently used in cost-utility analyses of tobacco control interventions. The goal of this study was to understand how researchers have addressed the methodological challenges involved in estimating these...

Full description

Bibliographic Details
Main Authors: Shari P. Feirman, Allison M. Glasser, Lyubov Teplitskaya, David R. Holtgrave, David B. Abrams, Raymond S. Niaura, Andrea C. Villanti
Format: Article
Language:English
Published: BMC 2016-07-01
Series:BMC Public Health
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12889-016-3319-z
_version_ 1811260250919010304
author Shari P. Feirman
Allison M. Glasser
Lyubov Teplitskaya
David R. Holtgrave
David B. Abrams
Raymond S. Niaura
Andrea C. Villanti
author_facet Shari P. Feirman
Allison M. Glasser
Lyubov Teplitskaya
David R. Holtgrave
David B. Abrams
Raymond S. Niaura
Andrea C. Villanti
author_sort Shari P. Feirman
collection DOAJ
description Abstract Background Estimated medical costs (“T”) and QALYs (“Q”) associated with smoking are frequently used in cost-utility analyses of tobacco control interventions. The goal of this study was to understand how researchers have addressed the methodological challenges involved in estimating these parameters. Methods Data were collected as part of a systematic review of tobacco modeling studies. We searched five electronic databases on July 1, 2013 with no date restrictions and synthesized studies qualitatively. Studies were eligible for the current analysis if they were U.S.-based, provided an estimate for Q, and used a societal perspective and lifetime analytic horizon to estimate T. We identified common methods and frequently cited sources used to obtain these estimates. Results Across all 18 studies included in this review, 50 % cited a 1992 source to estimate the medical costs associated with smoking and 56 % cited a 1996 study to derive the estimate for QALYs saved by quitting or preventing smoking. Approaches for estimating T varied dramatically among the studies included in this review. T was valued as a positive number, negative number and $0; five studies did not include estimates for T in their analyses. The most commonly cited source for Q based its estimate on the Health Utilities Index (HUI). Several papers also cited sources that based their estimates for Q on the Quality of Well-Being Scale and the EuroQol five dimensions questionnaire (EQ-5D). Conclusions Current estimates of the lifetime medical care costs and the QALYs associated with smoking are dated and do not reflect the latest evidence on the health effects of smoking, nor the current costs and benefits of smoking cessation and prevention. Given these limitations, we recommend that researchers conducting economic evaluations of tobacco control interventions perform extensive sensitivity analyses around these parameter estimates.
first_indexed 2024-04-12T18:44:37Z
format Article
id doaj.art-ac3f4d7fa13a4813938f6efc1e0cb2ee
institution Directory Open Access Journal
issn 1471-2458
language English
last_indexed 2024-04-12T18:44:37Z
publishDate 2016-07-01
publisher BMC
record_format Article
series BMC Public Health
spelling doaj.art-ac3f4d7fa13a4813938f6efc1e0cb2ee2022-12-22T03:20:40ZengBMCBMC Public Health1471-24582016-07-0116111110.1186/s12889-016-3319-zMedical costs and quality-adjusted life years associated with smoking: a systematic reviewShari P. Feirman0Allison M. Glasser1Lyubov Teplitskaya2David R. Holtgrave3David B. Abrams4Raymond S. Niaura5Andrea C. Villanti6The Schroeder Institute for Tobacco Research and Policy Studies at Truth InitiativeThe Schroeder Institute for Tobacco Research and Policy Studies at Truth InitiativeEvaluation Science and Research, Truth InitiativeDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public HealthThe Schroeder Institute for Tobacco Research and Policy Studies at Truth InitiativeThe Schroeder Institute for Tobacco Research and Policy Studies at Truth InitiativeThe Schroeder Institute for Tobacco Research and Policy Studies at Truth InitiativeAbstract Background Estimated medical costs (“T”) and QALYs (“Q”) associated with smoking are frequently used in cost-utility analyses of tobacco control interventions. The goal of this study was to understand how researchers have addressed the methodological challenges involved in estimating these parameters. Methods Data were collected as part of a systematic review of tobacco modeling studies. We searched five electronic databases on July 1, 2013 with no date restrictions and synthesized studies qualitatively. Studies were eligible for the current analysis if they were U.S.-based, provided an estimate for Q, and used a societal perspective and lifetime analytic horizon to estimate T. We identified common methods and frequently cited sources used to obtain these estimates. Results Across all 18 studies included in this review, 50 % cited a 1992 source to estimate the medical costs associated with smoking and 56 % cited a 1996 study to derive the estimate for QALYs saved by quitting or preventing smoking. Approaches for estimating T varied dramatically among the studies included in this review. T was valued as a positive number, negative number and $0; five studies did not include estimates for T in their analyses. The most commonly cited source for Q based its estimate on the Health Utilities Index (HUI). Several papers also cited sources that based their estimates for Q on the Quality of Well-Being Scale and the EuroQol five dimensions questionnaire (EQ-5D). Conclusions Current estimates of the lifetime medical care costs and the QALYs associated with smoking are dated and do not reflect the latest evidence on the health effects of smoking, nor the current costs and benefits of smoking cessation and prevention. Given these limitations, we recommend that researchers conducting economic evaluations of tobacco control interventions perform extensive sensitivity analyses around these parameter estimates.http://link.springer.com/article/10.1186/s12889-016-3319-zSmokingQALYMedical costs
spellingShingle Shari P. Feirman
Allison M. Glasser
Lyubov Teplitskaya
David R. Holtgrave
David B. Abrams
Raymond S. Niaura
Andrea C. Villanti
Medical costs and quality-adjusted life years associated with smoking: a systematic review
BMC Public Health
Smoking
QALY
Medical costs
title Medical costs and quality-adjusted life years associated with smoking: a systematic review
title_full Medical costs and quality-adjusted life years associated with smoking: a systematic review
title_fullStr Medical costs and quality-adjusted life years associated with smoking: a systematic review
title_full_unstemmed Medical costs and quality-adjusted life years associated with smoking: a systematic review
title_short Medical costs and quality-adjusted life years associated with smoking: a systematic review
title_sort medical costs and quality adjusted life years associated with smoking a systematic review
topic Smoking
QALY
Medical costs
url http://link.springer.com/article/10.1186/s12889-016-3319-z
work_keys_str_mv AT sharipfeirman medicalcostsandqualityadjustedlifeyearsassociatedwithsmokingasystematicreview
AT allisonmglasser medicalcostsandqualityadjustedlifeyearsassociatedwithsmokingasystematicreview
AT lyubovteplitskaya medicalcostsandqualityadjustedlifeyearsassociatedwithsmokingasystematicreview
AT davidrholtgrave medicalcostsandqualityadjustedlifeyearsassociatedwithsmokingasystematicreview
AT davidbabrams medicalcostsandqualityadjustedlifeyearsassociatedwithsmokingasystematicreview
AT raymondsniaura medicalcostsandqualityadjustedlifeyearsassociatedwithsmokingasystematicreview
AT andreacvillanti medicalcostsandqualityadjustedlifeyearsassociatedwithsmokingasystematicreview