Management of Upper-Limb Spasticity Using Modern Rehabilitation Techniques versus Botulinum Toxin Injections Following Stroke
Our purpose is to emphasize the role of botulinum toxin in spasticity therapy and functional recovery in patients following strokes. Our retrospective study compared two groups, namely ischemic and hemorrhagic stroke patients. The study group (BT group) comprised 80 patients who received focal botul...
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MDPI AG
2023-11-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/11/2218 |
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| author | Ana Maria Bumbea Otilia Constantina Rogoveanu Adina Turcu-Stiolica Ionica Pirici George Cioroianu Diana Iulia Stanca Oana Criciotoiu Viorel Biciusca Rodica Magdalena Traistaru Danut Visarion Caimac |
| author_facet | Ana Maria Bumbea Otilia Constantina Rogoveanu Adina Turcu-Stiolica Ionica Pirici George Cioroianu Diana Iulia Stanca Oana Criciotoiu Viorel Biciusca Rodica Magdalena Traistaru Danut Visarion Caimac |
| author_sort | Ana Maria Bumbea |
| collection | DOAJ |
| description | Our purpose is to emphasize the role of botulinum toxin in spasticity therapy and functional recovery in patients following strokes. Our retrospective study compared two groups, namely ischemic and hemorrhagic stroke patients. The study group (BT group) comprised 80 patients who received focal botulinum toxin as therapy for an upper limb with spastic muscle three times every three months. The control group (ES group) comprised 80 patients who received only medical rehabilitation consisting of electrostimulation and radial shockwave therapy for the upper limb, which was applied three times every three months. Both groups received the same stretching program for spastic muscles as a home training program. We evaluated the evolution of the patients using muscle strength, Ashworth, Tardieu, Frenchay, and Barthel scales. The analysis indicated a statistically significant difference between the two groups for all scales, with better results for the BT group (<i>p</i> < 0.0001 for all scales). In our study, the age at disease onset was an important prediction factor for better recovery in both groups but not in all scales. Better recovery was obtained for younger patients (in the BT group, MRC scale: rho = −0.609, <i>p</i>-value < 0.0001; Tardieu scale: rho = −0.365, <i>p</i>-value = 0.001; in the ES group, MRC scale: rho = −0.445, <i>p</i>-value < 0.0001; Barthel scale: rho = −0.239, <i>p</i>-value = 0.033). Our results demonstrated the effectiveness of botulinum toxin therapy compared with the rehabilitation method, showing a reduction of the recovery time of the upper limb, as well as an improvement of functionality and a reduction of disability. Although all patients followed a specific kinetic program, important improvements were evident in the botulinum toxin group. |
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| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-09T16:40:19Z |
| publishDate | 2023-11-01 |
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| spelling | doaj.art-ac42d00f66c94b9f97aa58e1f8c1bf9c2023-11-24T14:52:38ZengMDPI AGLife2075-17292023-11-011311221810.3390/life13112218Management of Upper-Limb Spasticity Using Modern Rehabilitation Techniques versus Botulinum Toxin Injections Following StrokeAna Maria Bumbea0Otilia Constantina Rogoveanu1Adina Turcu-Stiolica2Ionica Pirici3George Cioroianu4Diana Iulia Stanca5Oana Criciotoiu6Viorel Biciusca7Rodica Magdalena Traistaru8Danut Visarion Caimac9Department of Physical Medicine and Rehabilitation, University of Medicine and Pharmacy of Craiova, Petru Rares 2, 200349 Craiova, RomaniaDepartment of Physical Medicine and Rehabilitation, University of Medicine and Pharmacy of Craiova, Petru Rares 2, 200349 Craiova, RomaniaDepartment of Pharmacoeconomics, University of Medicine and Pharmacy of Craiova, Petru Rares 2, 200349 Craiova, RomaniaDepartment of Anatomy, University of Medicine and Pharmacy of Craiova, Petru Rares 2, 200349 Craiova, RomaniaDoctoral School, University of Medicine and Pharmacy of Craiova, Petru Rares 2, 200349 Craiova, RomaniaDepartment of Neurology, University of Medicine and Pharmacy of Craiova, Petru Rares 2, 200349 Craiova, RomaniaDepartment of Neurology, University of Medicine and Pharmacy of Craiova, Petru Rares 2, 200349 Craiova, RomaniaDepartment of Internal Medicine, University of Medicine and Pharmacy of Craiova, Petru Rares 2, 200349 Craiova, RomaniaMedical Rehabilitation Department, Nursing Faculty, University of Medicine and Pharmacy, Petru Rares 2, 200349 Craiova, RomaniaMedical Rehabilitation Department, Nursing Faculty, University of Medicine and Pharmacy, Petru Rares 2, 200349 Craiova, RomaniaOur purpose is to emphasize the role of botulinum toxin in spasticity therapy and functional recovery in patients following strokes. Our retrospective study compared two groups, namely ischemic and hemorrhagic stroke patients. The study group (BT group) comprised 80 patients who received focal botulinum toxin as therapy for an upper limb with spastic muscle three times every three months. The control group (ES group) comprised 80 patients who received only medical rehabilitation consisting of electrostimulation and radial shockwave therapy for the upper limb, which was applied three times every three months. Both groups received the same stretching program for spastic muscles as a home training program. We evaluated the evolution of the patients using muscle strength, Ashworth, Tardieu, Frenchay, and Barthel scales. The analysis indicated a statistically significant difference between the two groups for all scales, with better results for the BT group (<i>p</i> < 0.0001 for all scales). In our study, the age at disease onset was an important prediction factor for better recovery in both groups but not in all scales. Better recovery was obtained for younger patients (in the BT group, MRC scale: rho = −0.609, <i>p</i>-value < 0.0001; Tardieu scale: rho = −0.365, <i>p</i>-value = 0.001; in the ES group, MRC scale: rho = −0.445, <i>p</i>-value < 0.0001; Barthel scale: rho = −0.239, <i>p</i>-value = 0.033). Our results demonstrated the effectiveness of botulinum toxin therapy compared with the rehabilitation method, showing a reduction of the recovery time of the upper limb, as well as an improvement of functionality and a reduction of disability. Although all patients followed a specific kinetic program, important improvements were evident in the botulinum toxin group.https://www.mdpi.com/2075-1729/13/11/2218strokespasticitybotulinum toxinupper limb |
| spellingShingle | Ana Maria Bumbea Otilia Constantina Rogoveanu Adina Turcu-Stiolica Ionica Pirici George Cioroianu Diana Iulia Stanca Oana Criciotoiu Viorel Biciusca Rodica Magdalena Traistaru Danut Visarion Caimac Management of Upper-Limb Spasticity Using Modern Rehabilitation Techniques versus Botulinum Toxin Injections Following Stroke Life stroke spasticity botulinum toxin upper limb |
| title | Management of Upper-Limb Spasticity Using Modern Rehabilitation Techniques versus Botulinum Toxin Injections Following Stroke |
| title_full | Management of Upper-Limb Spasticity Using Modern Rehabilitation Techniques versus Botulinum Toxin Injections Following Stroke |
| title_fullStr | Management of Upper-Limb Spasticity Using Modern Rehabilitation Techniques versus Botulinum Toxin Injections Following Stroke |
| title_full_unstemmed | Management of Upper-Limb Spasticity Using Modern Rehabilitation Techniques versus Botulinum Toxin Injections Following Stroke |
| title_short | Management of Upper-Limb Spasticity Using Modern Rehabilitation Techniques versus Botulinum Toxin Injections Following Stroke |
| title_sort | management of upper limb spasticity using modern rehabilitation techniques versus botulinum toxin injections following stroke |
| topic | stroke spasticity botulinum toxin upper limb |
| url | https://www.mdpi.com/2075-1729/13/11/2218 |
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