Coronary Centerline Extraction from CCTA Using 3D-UNet

The mesh-type coronary model, obtained from three-dimensional reconstruction using the sequence of images produced by computed tomography (CT), can be used to obtain useful diagnostic information, such as extracting the projection of the lumen (planar development along an artery). In this paper, we...

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Main Authors: Alexandru Dorobanțiu, Valentin Ogrean, Remus Brad
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Future Internet
Subjects:
Online Access:https://www.mdpi.com/1999-5903/13/4/101
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author Alexandru Dorobanțiu
Valentin Ogrean
Remus Brad
author_facet Alexandru Dorobanțiu
Valentin Ogrean
Remus Brad
author_sort Alexandru Dorobanțiu
collection DOAJ
description The mesh-type coronary model, obtained from three-dimensional reconstruction using the sequence of images produced by computed tomography (CT), can be used to obtain useful diagnostic information, such as extracting the projection of the lumen (planar development along an artery). In this paper, we have focused on automated coronary centerline extraction from cardiac computed tomography angiography (CCTA) proposing a 3D version of U-Net architecture, trained with a novel loss function and with augmented patches. We have obtained promising results for accuracy (between 90–95%) and overlap (between 90–94%) with various network training configurations on the data from the Rotterdam Coronary Artery Centerline Extraction benchmark. We have also demonstrated the ability of the proposed network to learn despite the huge class imbalance and sparse annotation present in the training data.
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spelling doaj.art-ac485693cc374c018dff67a9460c95822023-11-21T16:11:34ZengMDPI AGFuture Internet1999-59032021-04-0113410110.3390/fi13040101Coronary Centerline Extraction from CCTA Using 3D-UNetAlexandru Dorobanțiu0Valentin Ogrean1Remus Brad2Computer Science and Electrical Engineering Department, Lucian Blaga University of Sibiu, 550024 Sibiu, RomaniaComputer Science and Electrical Engineering Department, Lucian Blaga University of Sibiu, 550024 Sibiu, RomaniaComputer Science and Electrical Engineering Department, Lucian Blaga University of Sibiu, 550024 Sibiu, RomaniaThe mesh-type coronary model, obtained from three-dimensional reconstruction using the sequence of images produced by computed tomography (CT), can be used to obtain useful diagnostic information, such as extracting the projection of the lumen (planar development along an artery). In this paper, we have focused on automated coronary centerline extraction from cardiac computed tomography angiography (CCTA) proposing a 3D version of U-Net architecture, trained with a novel loss function and with augmented patches. We have obtained promising results for accuracy (between 90–95%) and overlap (between 90–94%) with various network training configurations on the data from the Rotterdam Coronary Artery Centerline Extraction benchmark. We have also demonstrated the ability of the proposed network to learn despite the huge class imbalance and sparse annotation present in the training data.https://www.mdpi.com/1999-5903/13/4/101CCTAcenterlinecoronary artery segmentationdeep learningU-NET
spellingShingle Alexandru Dorobanțiu
Valentin Ogrean
Remus Brad
Coronary Centerline Extraction from CCTA Using 3D-UNet
Future Internet
CCTA
centerline
coronary artery segmentation
deep learning
U-NET
title Coronary Centerline Extraction from CCTA Using 3D-UNet
title_full Coronary Centerline Extraction from CCTA Using 3D-UNet
title_fullStr Coronary Centerline Extraction from CCTA Using 3D-UNet
title_full_unstemmed Coronary Centerline Extraction from CCTA Using 3D-UNet
title_short Coronary Centerline Extraction from CCTA Using 3D-UNet
title_sort coronary centerline extraction from ccta using 3d unet
topic CCTA
centerline
coronary artery segmentation
deep learning
U-NET
url https://www.mdpi.com/1999-5903/13/4/101
work_keys_str_mv AT alexandrudorobantiu coronarycenterlineextractionfromcctausing3dunet
AT valentinogrean coronarycenterlineextractionfromcctausing3dunet
AT remusbrad coronarycenterlineextractionfromcctausing3dunet