Adult zebrafish Langerhans cells arise from hematopoietic stem/progenitor cells

Adult zebrafish Langerhans cells arise from hematopoietic stem/progenitor cells

The origin of Langerhans cells (LCs), which are skin epidermis-resident macrophages, remains unclear. Current lineage tracing of LCs largely relies on the promoter-Cre-LoxP system, which often gives rise to contradictory conclusions with different promoters. Thus, reinvestigation with an improved tr...

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Bibliographic Details
Main Authors: Sicong He, Jiahao Chen, Yunyun Jiang, Yi Wu, Lu Zhu, Wan Jin, Changlong Zhao, Tao Yu, Tienan Wang, Shuting Wu, Xi Lin, Jianan Y Qu, Zilong Wen, Wenqing Zhang, Jin Xu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-06-01
Series:eLife
Subjects:
Langerhans cell
tissue resident macrophage
lineage tracing
zebrafish
Online Access:https://elifesciences.org/articles/36131

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