Characterization of the In Vivo and In Vitro Metabolites of Linarin in Rat Biosamples and Intestinal Flora Using Ultra-High Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Tandem Mass Spectrometry

Characterization of the In Vivo and In Vitro Metabolites of Linarin in Rat Biosamples and Intestinal Flora Using Ultra-High Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Tandem Mass Spectrometry

Linarin, a flavone glycoside, is considered to be a promising natural product due to its diverse pharmacological activities, including analgesic, antipyretic, anti-inflammatory and hepatoprotective activities. In this research, the metabolites of linarin in rat intestinal flora and biosamples were c...

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Bibliographic Details
Main Authors: Xinchi Feng, Yang Li, Chenxi Guang, Miao Qiao, Tong Wang, Liwei Chai, Feng Qiu
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Molecules
Subjects:
linarin
ring cleavage metabolites
UPLC/Q-TOF-MS/MS
rats
intestinal flora
Online Access:http://www.mdpi.com/1420-3049/23/9/2140

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