575 Dual blockade of LAG3 and TIGIT improves the treatment efficacy of a nanoparticle-mediated immunoradiation in anti-PD1 resistant lung cancer in mice
Main Authors: | , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2021-11-01
|
Series: | Journal for ImmunoTherapy of Cancer |
_version_ | 1798026862355546112 |
---|---|
author | James Welsh Sébastien Paris Hampartsoum Barsoumian Yun Hu Mark Wasley Liangpeng Yang Quynh-Nhu Nguyen Fatemeh Masrorpour Saumil Gandhi Genevieve Bertolet Lily Schuda Kewen He Duygu Sezen Joylise Mitchell Tiffany Voss SILVA Jordan Claudia Kettlun Leyton Nahum Puebla-Osorio Angelica Cortez |
author_facet | James Welsh Sébastien Paris Hampartsoum Barsoumian Yun Hu Mark Wasley Liangpeng Yang Quynh-Nhu Nguyen Fatemeh Masrorpour Saumil Gandhi Genevieve Bertolet Lily Schuda Kewen He Duygu Sezen Joylise Mitchell Tiffany Voss SILVA Jordan Claudia Kettlun Leyton Nahum Puebla-Osorio Angelica Cortez |
author_sort | James Welsh |
collection | DOAJ |
first_indexed | 2024-04-11T18:42:14Z |
format | Article |
id | doaj.art-ac4c8f454ce64995a234fdcb51a58ba6 |
institution | Directory Open Access Journal |
issn | 2051-1426 |
language | English |
last_indexed | 2024-04-11T18:42:14Z |
publishDate | 2021-11-01 |
publisher | BMJ Publishing Group |
record_format | Article |
series | Journal for ImmunoTherapy of Cancer |
spelling | doaj.art-ac4c8f454ce64995a234fdcb51a58ba62022-12-22T04:08:57ZengBMJ Publishing GroupJournal for ImmunoTherapy of Cancer2051-14262021-11-019Suppl 210.1136/jitc-2021-SITC2021.575575 Dual blockade of LAG3 and TIGIT improves the treatment efficacy of a nanoparticle-mediated immunoradiation in anti-PD1 resistant lung cancer in miceJames Welsh0Sébastien Paris1Hampartsoum Barsoumian2Yun Hu3Mark Wasley4Liangpeng Yang5Quynh-Nhu Nguyen6Fatemeh Masrorpour7Saumil Gandhi8Genevieve Bertolet9Lily Schuda10Kewen He11Duygu Sezen12Joylise Mitchell13Tiffany Voss14SILVA Jordan15Claudia Kettlun Leyton16Nahum Puebla-Osorio17Angelica Cortez181MD Anderson Cancer Center, Houston, TX, USA2Nanobiotix, Paris, France1MD Anderson Cancer Center, Houston, TX, USA1MD Anderson Cancer Center, Houston, TX, USA1MD Anderson Cancer Center, Houston, TX, USA2 Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USARadiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, United StatesRadiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA1MD Anderson Cancer Center, Houston, TX, USA1MD Anderson Cancer Center, Houston, TX, USA1MD Anderson Cancer Center, Houston, TX, USA1MD Anderson Cancer Center, Houston, TX, USA1MD Anderson Cancer Center, Houston, TX, USA1MD Anderson Cancer Center, Houston, TX, USA1MD Anderson Cancer Center, Houston, TX, USA2Nanobiotix, Paris, France1MD Anderson Cancer Center, Houston, TX, USA1MD Anderson Cancer Center, Houston, TX, USA1MD Anderson Cancer Center, Houston, TX, USA |
spellingShingle | James Welsh Sébastien Paris Hampartsoum Barsoumian Yun Hu Mark Wasley Liangpeng Yang Quynh-Nhu Nguyen Fatemeh Masrorpour Saumil Gandhi Genevieve Bertolet Lily Schuda Kewen He Duygu Sezen Joylise Mitchell Tiffany Voss SILVA Jordan Claudia Kettlun Leyton Nahum Puebla-Osorio Angelica Cortez 575 Dual blockade of LAG3 and TIGIT improves the treatment efficacy of a nanoparticle-mediated immunoradiation in anti-PD1 resistant lung cancer in mice Journal for ImmunoTherapy of Cancer |
title | 575 Dual blockade of LAG3 and TIGIT improves the treatment efficacy of a nanoparticle-mediated immunoradiation in anti-PD1 resistant lung cancer in mice |
title_full | 575 Dual blockade of LAG3 and TIGIT improves the treatment efficacy of a nanoparticle-mediated immunoradiation in anti-PD1 resistant lung cancer in mice |
title_fullStr | 575 Dual blockade of LAG3 and TIGIT improves the treatment efficacy of a nanoparticle-mediated immunoradiation in anti-PD1 resistant lung cancer in mice |
title_full_unstemmed | 575 Dual blockade of LAG3 and TIGIT improves the treatment efficacy of a nanoparticle-mediated immunoradiation in anti-PD1 resistant lung cancer in mice |
title_short | 575 Dual blockade of LAG3 and TIGIT improves the treatment efficacy of a nanoparticle-mediated immunoradiation in anti-PD1 resistant lung cancer in mice |
title_sort | 575 dual blockade of lag3 and tigit improves the treatment efficacy of a nanoparticle mediated immunoradiation in anti pd1 resistant lung cancer in mice |
work_keys_str_mv | AT jameswelsh 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT sebastienparis 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT hampartsoumbarsoumian 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT yunhu 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT markwasley 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT liangpengyang 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT quynhnhunguyen 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT fatemehmasrorpour 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT saumilgandhi 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT genevievebertolet 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT lilyschuda 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT kewenhe 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT duygusezen 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT joylisemitchell 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT tiffanyvoss 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT silvajordan 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT claudiakettlunleyton 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT nahumpueblaosorio 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice AT angelicacortez 575dualblockadeoflag3andtigitimprovesthetreatmentefficacyofananoparticlemediatedimmunoradiationinantipd1resistantlungcancerinmice |