Overview of Plasma and Platelet Transfusions in Critically Ill Children
Critically ill children are a unique population who frequently receive plasma and platelet transfusions for both active bleeding and mitigation of bleeding risk. While these products are frequently administered, transfusion indications in this population remain unclear, and practice varies across in...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-11-01
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| Series: | Frontiers in Pediatrics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2020.601659/full |
| _version_ | 1818244430682914816 |
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| author | Stacie Kahn Madhuradhar Chegondi Marianne E. Nellis Oliver Karam |
| author_facet | Stacie Kahn Madhuradhar Chegondi Marianne E. Nellis Oliver Karam |
| author_sort | Stacie Kahn |
| collection | DOAJ |
| description | Critically ill children are a unique population who frequently receive plasma and platelet transfusions for both active bleeding and mitigation of bleeding risk. While these products are frequently administered, transfusion indications in this population remain unclear, and practice varies across institutions and providers. In this manuscript, we will outline the current evidence regarding plasma and platelet transfusions for hemostasis in the pediatric intensive care setting. For both products, we will describe the product composition, epidemiology, and product indications and discuss the potential risks and benefits involved with the transfusion. We will also discuss knowledge gaps and future areas of research. |
| first_indexed | 2024-12-12T14:16:54Z |
| format | Article |
| id | doaj.art-ac4f96528fc144c79bf9799ec4b6888a |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-12-12T14:16:54Z |
| publishDate | 2020-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-ac4f96528fc144c79bf9799ec4b6888a2022-12-22T00:21:54ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602020-11-01810.3389/fped.2020.601659601659Overview of Plasma and Platelet Transfusions in Critically Ill ChildrenStacie Kahn0Madhuradhar Chegondi1Marianne E. Nellis2Oliver Karam3Division of Pediatric Critical Care Medicine, NewYork-Presbyterian, Morgan Stanley Children's Hospital, New York, NY, United StatesDivision of Pediatric Critical Care Medicine, Stead Family Children's Hospital- Carver College of Medicine, University of Iowa, Iowa, IA, United StatesPediatric Critical Care Medicine, NewYork-Presbyterian Hospital – Weill Cornell Medicine, New York, NY, United StatesDivision of Pediatric Critical Care Medicine, Children's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA, United StatesCritically ill children are a unique population who frequently receive plasma and platelet transfusions for both active bleeding and mitigation of bleeding risk. While these products are frequently administered, transfusion indications in this population remain unclear, and practice varies across institutions and providers. In this manuscript, we will outline the current evidence regarding plasma and platelet transfusions for hemostasis in the pediatric intensive care setting. For both products, we will describe the product composition, epidemiology, and product indications and discuss the potential risks and benefits involved with the transfusion. We will also discuss knowledge gaps and future areas of research.https://www.frontiersin.org/articles/10.3389/fped.2020.601659/fullplatelet transfusionplasmacritical ill childrenhemostasishemorrhage |
| spellingShingle | Stacie Kahn Madhuradhar Chegondi Marianne E. Nellis Oliver Karam Overview of Plasma and Platelet Transfusions in Critically Ill Children Frontiers in Pediatrics platelet transfusion plasma critical ill children hemostasis hemorrhage |
| title | Overview of Plasma and Platelet Transfusions in Critically Ill Children |
| title_full | Overview of Plasma and Platelet Transfusions in Critically Ill Children |
| title_fullStr | Overview of Plasma and Platelet Transfusions in Critically Ill Children |
| title_full_unstemmed | Overview of Plasma and Platelet Transfusions in Critically Ill Children |
| title_short | Overview of Plasma and Platelet Transfusions in Critically Ill Children |
| title_sort | overview of plasma and platelet transfusions in critically ill children |
| topic | platelet transfusion plasma critical ill children hemostasis hemorrhage |
| url | https://www.frontiersin.org/articles/10.3389/fped.2020.601659/full |
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