Efficacy and safety of the first made in Russia alpha, beta long-acting adrenoblocker proxodolol in patients with arterial hypertension of the second degree
Aim. To study efficacy and safety of a new dose and dosage form of proxodolol - a beta-adrenoblocker with alpha1-adrenoblocking activity - in patients with moderate arterial hypertension (AH). Material and methods. A total of 60 patients with verified diagnosis of essential AH of the second degree w...
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| Format: | Article |
| Language: | Russian |
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"Consilium Medicum" Publishing house
2011-04-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/30848 |
| _version_ | 1818326585423429632 |
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| author | S A Belyaeva S A Belyaeva |
| author_facet | S A Belyaeva S A Belyaeva |
| author_sort | S A Belyaeva |
| collection | DOAJ |
| description | Aim. To study efficacy and safety of a new dose and dosage form of proxodolol - a beta-adrenoblocker with alpha1-adrenoblocking activity - in patients with moderate arterial hypertension (AH).
Material and methods. A total of 60 patients with verified diagnosis of essential AH of the second degree were randomized into two groups: group 1 (n = 40) received proxodolol, group 2 (n = 20) was given carvedilol. The trial lasted for 89 days.
Results. The trial demonstrates that proxodolol is highly effective and safe in the treatment of AH.
Conclusion. Proxodolol is effective and safe in hypertension, in a dose 120 mg its activity is the same as carvedilol in a dose 25 mg. |
| first_indexed | 2024-12-13T12:02:43Z |
| format | Article |
| id | doaj.art-ac5025f8cf2a48c3b7ef48674c34eb86 |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-13T12:02:43Z |
| publishDate | 2011-04-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-ac5025f8cf2a48c3b7ef48674c34eb862022-12-21T23:47:03Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422011-04-01834525527864Efficacy and safety of the first made in Russia alpha, beta long-acting adrenoblocker proxodolol in patients with arterial hypertension of the second degreeS A BelyaevaS A Belyaeva0Research Center for Biomedical technologies, Moscow;"Medsantrud" hospital N 23, MoscowAim. To study efficacy and safety of a new dose and dosage form of proxodolol - a beta-adrenoblocker with alpha1-adrenoblocking activity - in patients with moderate arterial hypertension (AH). Material and methods. A total of 60 patients with verified diagnosis of essential AH of the second degree were randomized into two groups: group 1 (n = 40) received proxodolol, group 2 (n = 20) was given carvedilol. The trial lasted for 89 days. Results. The trial demonstrates that proxodolol is highly effective and safe in the treatment of AH. Conclusion. Proxodolol is effective and safe in hypertension, in a dose 120 mg its activity is the same as carvedilol in a dose 25 mg.https://ter-arkhiv.ru/0040-3660/article/view/30848arterial hypertensionbeta-adrenoblockerscarvedilolproxodolol |
| spellingShingle | S A Belyaeva S A Belyaeva Efficacy and safety of the first made in Russia alpha, beta long-acting adrenoblocker proxodolol in patients with arterial hypertension of the second degree Терапевтический архив arterial hypertension beta-adrenoblockers carvedilol proxodolol |
| title | Efficacy and safety of the first made in Russia alpha, beta long-acting adrenoblocker proxodolol in patients with arterial hypertension of the second degree |
| title_full | Efficacy and safety of the first made in Russia alpha, beta long-acting adrenoblocker proxodolol in patients with arterial hypertension of the second degree |
| title_fullStr | Efficacy and safety of the first made in Russia alpha, beta long-acting adrenoblocker proxodolol in patients with arterial hypertension of the second degree |
| title_full_unstemmed | Efficacy and safety of the first made in Russia alpha, beta long-acting adrenoblocker proxodolol in patients with arterial hypertension of the second degree |
| title_short | Efficacy and safety of the first made in Russia alpha, beta long-acting adrenoblocker proxodolol in patients with arterial hypertension of the second degree |
| title_sort | efficacy and safety of the first made in russia alpha beta long acting adrenoblocker proxodolol in patients with arterial hypertension of the second degree |
| topic | arterial hypertension beta-adrenoblockers carvedilol proxodolol |
| url | https://ter-arkhiv.ru/0040-3660/article/view/30848 |
| work_keys_str_mv | AT sabelyaeva efficacyandsafetyofthefirstmadeinrussiaalphabetalongactingadrenoblockerproxodololinpatientswitharterialhypertensionoftheseconddegree AT sabelyaeva efficacyandsafetyofthefirstmadeinrussiaalphabetalongactingadrenoblockerproxodololinpatientswitharterialhypertensionoftheseconddegree |