Fixed and separate combination of solifenacin and tamsulosin in urinary disorders associated with benign prostatic hyperplasia: a choice based on price and value comparison

Objective. To determine the consequences of the use of a fi xed combination of solifenacin and tamsulosin in patients whom recommended the prescription of these drugs. Methods. Analysis of prices of drugs solifenacin + tamsulosin controlled release (Vasomni), solifenacin (Vesicare), tamsulosin contr...

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Main Authors: A. G. Tolkushin, A. V. Smirnova, T. N. Ermolaeva, M. V. Davidovsky
Format: Article
Language:Russian
Published: Izdatelstvo OKI 2019-08-01
Series:Качественная клиническая практика
Subjects:
Online Access:https://www.clinvest.ru/jour/article/view/435
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author A. G. Tolkushin
A. V. Smirnova
T. N. Ermolaeva
M. V. Davidovsky
author_facet A. G. Tolkushin
A. V. Smirnova
T. N. Ermolaeva
M. V. Davidovsky
author_sort A. G. Tolkushin
collection DOAJ
description Objective. To determine the consequences of the use of a fi xed combination of solifenacin and tamsulosin in patients whom recommended the prescription of these drugs. Methods. Analysis of prices of drugs solifenacin + tamsulosin controlled release (Vasomni), solifenacin (Vesicare), tamsulosin controlled release (Omnic Okas) and tamsulosin modifi ed-release (several registered trade names of the drug) conducted on the basis of information from several sources: 1 — the register of maximum ex-works prices of manufacturers of vital and essential medicines, 2 — data on average prices in pharmacies of Moscow (as of 15.02.2018), 3 — weighted average prices of public procurement for 2018 according to the monitoring of the pharmaceutical market. To determine the points of relative value of drugs, a survey of experts was conducted: 1 — to determine the values of the criteria for the drugs under consideration — urologists; 2 — to determine the weight of the criteria — persons involved in the decision-making on the selection and purchase of drugs. Results. We found that the cost of the equivalent course dose of Vesomni was on 40-42 % lower than the combination of drugs Vesicar and Omnik Okas. Compared with the non-fi xed combination of solifenacin with tamsulosin in a drug form with modifi ed release, no signifi cant diff erences in price levels were found. At the same time, the relative value of a fi xed combination is 5-6 percentage points higher compared to non-fi xed combinations, mainly due to ease of use. Conclusion. Use of a fi xed combination of solifenacin + tamsulosin can lead to budget savings with an increase in the level of relative value.
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spelling doaj.art-ac51088e3e8440ddb6b67144bda563232024-03-14T18:09:08ZrusIzdatelstvo OKIКачественная клиническая практика2588-05192618-84732019-08-0101121810.24411/2588-0519-2019-10060431Fixed and separate combination of solifenacin and tamsulosin in urinary disorders associated with benign prostatic hyperplasia: a choice based on price and value comparisonA. G. Tolkushin0A. V. Smirnova1T. N. Ermolaeva2M. V. Davidovsky3ГБУ «НПЦ КИОМТ ДЗМ»ГБУ «НПЦ КИОМТ ДЗМ»ГБУ «НПЦ КИОМТ ДЗМ»ГБУ «НПЦ КИОМТ ДЗМ»Objective. To determine the consequences of the use of a fi xed combination of solifenacin and tamsulosin in patients whom recommended the prescription of these drugs. Methods. Analysis of prices of drugs solifenacin + tamsulosin controlled release (Vasomni), solifenacin (Vesicare), tamsulosin controlled release (Omnic Okas) and tamsulosin modifi ed-release (several registered trade names of the drug) conducted on the basis of information from several sources: 1 — the register of maximum ex-works prices of manufacturers of vital and essential medicines, 2 — data on average prices in pharmacies of Moscow (as of 15.02.2018), 3 — weighted average prices of public procurement for 2018 according to the monitoring of the pharmaceutical market. To determine the points of relative value of drugs, a survey of experts was conducted: 1 — to determine the values of the criteria for the drugs under consideration — urologists; 2 — to determine the weight of the criteria — persons involved in the decision-making on the selection and purchase of drugs. Results. We found that the cost of the equivalent course dose of Vesomni was on 40-42 % lower than the combination of drugs Vesicar and Omnik Okas. Compared with the non-fi xed combination of solifenacin with tamsulosin in a drug form with modifi ed release, no signifi cant diff erences in price levels were found. At the same time, the relative value of a fi xed combination is 5-6 percentage points higher compared to non-fi xed combinations, mainly due to ease of use. Conclusion. Use of a fi xed combination of solifenacin + tamsulosin can lead to budget savings with an increase in the level of relative value.https://www.clinvest.ru/jour/article/view/435солифенацинтамсулозинклинико-экономический анализценаценностьфармакоэкономическое исследованиедоброкачественная гиперплазия предстательной железысимптомы нижних мочевых путей
spellingShingle A. G. Tolkushin
A. V. Smirnova
T. N. Ermolaeva
M. V. Davidovsky
Fixed and separate combination of solifenacin and tamsulosin in urinary disorders associated with benign prostatic hyperplasia: a choice based on price and value comparison
Качественная клиническая практика
солифенацин
тамсулозин
клинико-экономический анализ
цена
ценность
фармакоэкономическое исследование
доброкачественная гиперплазия предстательной железы
симптомы нижних мочевых путей
title Fixed and separate combination of solifenacin and tamsulosin in urinary disorders associated with benign prostatic hyperplasia: a choice based on price and value comparison
title_full Fixed and separate combination of solifenacin and tamsulosin in urinary disorders associated with benign prostatic hyperplasia: a choice based on price and value comparison
title_fullStr Fixed and separate combination of solifenacin and tamsulosin in urinary disorders associated with benign prostatic hyperplasia: a choice based on price and value comparison
title_full_unstemmed Fixed and separate combination of solifenacin and tamsulosin in urinary disorders associated with benign prostatic hyperplasia: a choice based on price and value comparison
title_short Fixed and separate combination of solifenacin and tamsulosin in urinary disorders associated with benign prostatic hyperplasia: a choice based on price and value comparison
title_sort fixed and separate combination of solifenacin and tamsulosin in urinary disorders associated with benign prostatic hyperplasia a choice based on price and value comparison
topic солифенацин
тамсулозин
клинико-экономический анализ
цена
ценность
фармакоэкономическое исследование
доброкачественная гиперплазия предстательной железы
симптомы нижних мочевых путей
url https://www.clinvest.ru/jour/article/view/435
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AT avsmirnova fixedandseparatecombinationofsolifenacinandtamsulosininurinarydisordersassociatedwithbenignprostatichyperplasiaachoicebasedonpriceandvaluecomparison
AT tnermolaeva fixedandseparatecombinationofsolifenacinandtamsulosininurinarydisordersassociatedwithbenignprostatichyperplasiaachoicebasedonpriceandvaluecomparison
AT mvdavidovsky fixedandseparatecombinationofsolifenacinandtamsulosininurinarydisordersassociatedwithbenignprostatichyperplasiaachoicebasedonpriceandvaluecomparison