Human embryos harbor complex mosaicism with broad presence of aneuploid cells during early development

Human embryos harbor complex mosaicism with broad presence of aneuploid cells during early development

Abstract Pre-implantation genetic testing for aneuploidy (PGT-A) is used in approximately half of in vitro fertilization cycles. Given the limited understanding of the genetics of human embryos, the current use of PGT-A is based on biologically uncertain assumptions and unvalidated guidelines, leadi...

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Bibliographic Details
Main Authors: Fan Zhai, Siming Kong, Shi Song, Qianying Guo, Ling Ding, Jiaqi Zhang, Nan Wang, Ying Kuo, Shuo Guan, Peng Yuan, Liying Yan, Zhiqiang Yan, Jie Qiao
Format: Article
Language:English
Published: Nature Publishing Group 2024-09-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-024-00719-3

Internet

https://doi.org/10.1038/s41421-024-00719-3

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