The Potential Antidepressant Action of Duloxetine Co-Administered with the TAAR1 Receptor Agonist SEP-363856 in Mice

The Potential Antidepressant Action of Duloxetine Co-Administered with the TAAR1 Receptor Agonist SEP-363856 in Mice

Here, we explored the possible interaction between duloxetine and SEP-363856 (SEP-856) in depression-related reactions. The results showed that oral administration of duloxetine showed powerful antidepressant-like effects in both the forced swimming test (FST) and the suspension tail test (TST). SEP...

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Bibliographic Details
Main Authors: Xia Ren, Jiaying Xiong, Lingzhi Liang, Yin Chen, Guisen Zhang
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
depression
duloxetine
SEP-363856
co-administration
antidepressant-like effect
Online Access:https://www.mdpi.com/1420-3049/27/9/2755

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