Unravelling cell type-specific responses to Parkinson’s Disease at single cell resolution

Unravelling cell type-specific responses to Parkinson’s Disease at single cell resolution

Abstract Parkinson’s Disease (PD) is the second most common neurodegenerative disorder. The pathological hallmark of PD is loss of dopaminergic neurons and the presence of aggregated α-synuclein, primarily in the substantia nigra pars compacta (SNpc) of the midbrain. However, the molecular mechanism...

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Main Authors: Araks Martirosyan, Rizwan Ansari, Francisco Pestana, Katja Hebestreit, Hayk Gasparyan, Razmik Aleksanyan, Silvia Hnatova, Suresh Poovathingal, Catherine Marneffe, Dietmar R. Thal, Andrew Kottick, Victor J. Hanson-Smith, Sebastian Guelfi, William Plumbly, T. Grant Belgard, Emmanouil Metzakopian, Matthew G. Holt
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Molecular Neurodegeneration
Online Access:https://doi.org/10.1186/s13024-023-00699-0

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https://doi.org/10.1186/s13024-023-00699-0

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