Parkin Promotes Mitophagic Cell Death in Adult Hippocampal Neural Stem Cells Following Insulin Withdrawal

Parkin Promotes Mitophagic Cell Death in Adult Hippocampal Neural Stem Cells Following Insulin Withdrawal

Regulated cell death (RCD) plays a fundamental role in human health and disease. Apoptosis is the best-studied mode of RCD, but the importance of other modes has recently been gaining attention. We have previously demonstrated that adult rat hippocampal neural stem (HCN) cells undergo autophagy-depe...

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Bibliographic Details
Main Authors: Hyunhee Park, Kyung Min Chung, Hyun-Kyu An, Ji-Eun Gim, Jihyun Hong, Hanwoong Woo, Bongki Cho, Cheil Moon, Seong-Woon Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
autophagy-dependent cell death
c-Jun
hippocampal neural stem cells
mitophagy
Parkin
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00046/full

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